loading...| Preferred Name |
Dextromethorphan Hydrobromide |
|
| Synonyms |
Dextromethorphan Hydrobromide DEXTROMETHORPHAN HYDROBROMIDE |
|
| Definitions |
The hydrobromide salt form of dextromethorphan, a synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C423 |
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| CAS_Registry |
6700-34-1 |
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| Chemical_Formula |
C18H25NO.BrH.H2O |
|
| code |
C423 |
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
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| Contributing_Source |
CTRP FDA |
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| DEFINITION |
The hydrobromide salt form of dextromethorphan, a synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex. |
|
| Display_Name |
Dextromethorphan Hydrobromide |
|
| FDA_UNII_Code |
9D2RTI9KYH |
|
| FULL_SYN |
Dextromethorphan Hydrobromide DEXTROMETHORPHAN HYDROBROMIDE |
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| Has_Free_Acid_Or_Base_Form | ||
| label |
Dextromethorphan Hydrobromide |
|
| Legacy Concept Name |
Dextromethorphan |
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| NCI_Drug_Dictionary_ID |
42490 |
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| PDQ_Closed_Trial_Search_ID |
42490 |
|
| PDQ_Open_Trial_Search_ID |
42490 |
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| Preferred_Name |
Dextromethorphan Hydrobromide |
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| prefixIRI |
Thesaurus:C423 |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
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| UMLS_CUI |
C0350422 |
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| subClassOf |