loading...| Preferred Name |
Mesalamine |
|
| Synonyms |
5-Amino-2-hydroxybenzoic Acid 5-Aminosalicylic Acid 5-ASA Apriso Asacol Lialda MESALAMINE Mesalamine Mesalazine Pentasa Rowasa |
|
| Definitions |
An agent derived from sulfasalazine, an antiinflammatory agent. Mesalamine may reduce inflammation through inhibition of cyclooxygenase and prostaglandin production. Following rectal or oral administration, only a small amount of mesalamine is absorbed; the remainder, acting topically, reduces bowel inflammation, diarrhea, rectal bleeding and stomach pain. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29249 |
|
| Accepted_Therapeutic_Use_For |
Ulcerative Colitis and Proctitis |
|
| CAS_Registry |
89-57-6 |
|
| CHEBI_ID |
CHEBI:6775 |
|
| Chemical_Formula |
C7H7NO3 |
|
| code |
C29249 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA |
|
| DEFINITION |
An agent derived from sulfasalazine, an antiinflammatory agent. Mesalamine may reduce inflammation through inhibition of cyclooxygenase and prostaglandin production. Following rectal or oral administration, only a small amount of mesalamine is absorbed; the remainder, acting topically, reduces bowel inflammation, diarrhea, rectal bleeding and stomach pain. (NCI04) |
|
| Display_Name |
Mesalamine |
|
| FDA_UNII_Code |
4Q81I59GXC |
|
| FULL_SYN |
5-Amino-2-hydroxybenzoic Acid 5-Aminosalicylic Acid 5-ASA Apriso Asacol Lialda MESALAMINE Mesalamine Mesalazine Pentasa Rowasa |
|
| label |
Mesalamine |
|
| Legacy Concept Name |
Mesalamine |
|
| NCI_Drug_Dictionary_ID |
732182 |
|
| NSC Number |
38877 |
|
| PDQ_Closed_Trial_Search_ID |
732182 |
|
| PDQ_Open_Trial_Search_ID |
732182 |
|
| Preferred_Name |
Mesalamine |
|
| prefixIRI |
Thesaurus:C29249 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0127615 |
|
| subClassOf |