loading...| Preferred Name |
Irbesartan |
|
| Synonyms |
Avapro IRBESARTAN Irbesartan |
|
| Definitions |
A nonpeptide angiotensin II antagonist with antihypertensive activity. Irbesartan selectively and competitively blocks the binding of angiotensin II to the angiotensin I receptor. Angiotensin II stimulates aldosterone synthesis and secretion by adrenal cortex, which decreases the excretion of sodium and increases the excretion of potassium. Angiotensin II also acts as a vasoconstrictor in vascular smooth muscle. (NCI05) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29130 |
|
| CAS_Registry |
138402-11-6 |
|
| CHEBI_ID |
CHEBI:5959 |
|
| Chemical_Formula |
C25H28N6O |
|
| code |
C29130 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 |
|
| Contributing_Source |
FDA |
|
| DEFINITION |
A nonpeptide angiotensin II antagonist with antihypertensive activity. Irbesartan selectively and competitively blocks the binding of angiotensin II to the angiotensin I receptor. Angiotensin II stimulates aldosterone synthesis and secretion by adrenal cortex, which decreases the excretion of sodium and increases the excretion of potassium. Angiotensin II also acts as a vasoconstrictor in vascular smooth muscle. (NCI05) |
|
| FDA_UNII_Code |
J0E2756Z7N |
|
| FULL_SYN |
Avapro IRBESARTAN Irbesartan |
|
| label |
Irbesartan |
|
| Legacy Concept Name |
Irbesartan |
|
| Preferred_Name |
Irbesartan |
|
| prefixIRI |
Thesaurus:C29130 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0595301 |
|
| subClassOf |