National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Dicloxacillin

Synonyms

Dicloxacillin

DICLOXACILLIN

3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin

Definitions

A broad-spectrum, semi-synthetic, beta-lactam, penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Dicloxacillin binds to penicillin binding proteins (PBP) located on the inner membrane of the bacterial cell wall. It also inhibits the cross-linkage of peptidoglycan, a critical component of bacterial cell walls. This leads to the inhibition of bacterial cell wall synthesis and eventually causes cell lysis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28986

CAS_Registry

3116-76-5

CHEBI_ID

CHEBI:4511

Chemical_Formula

C19H17Cl2N3O5S

code

C28986

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A broad-spectrum, semi-synthetic, beta-lactam, penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Dicloxacillin binds to penicillin binding proteins (PBP) located on the inner membrane of the bacterial cell wall. It also inhibits the cross-linkage of peptidoglycan, a critical component of bacterial cell walls. This leads to the inhibition of bacterial cell wall synthesis and eventually causes cell lysis.

FDA_UNII_Code

COF19H7WBK

FULL_SYN

Dicloxacillin

DICLOXACILLIN

3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47985

label

Dicloxacillin

Legacy Concept Name

Dicloxacillin

Preferred_Name

Dicloxacillin

prefixIRI

Thesaurus:C28986

Semantic_Type

Organic Chemical

Pharmacologic Substance

Antibiotic

UMLS_CUI

C0012093

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1500

Delete Subject Author Type Created
No notes to display
Create mapping

Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/SNMI/C-54430 SNMI LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015921 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/RXNORM/3356 RXNORM LOOM
http://purl.obolibrary.org/obo/ARO_3000635 ARO LOOM
https://go.drugbank.com/drugs/DB00485 MDM LOOM
http://purl.obolibrary.org/obo/OMIT_0005279 OMIT LOOM
http://purl.bioontology.org/ontology/ATC/J01CF01 ATC LOOM
http://purl.bioontology.org/ontology/MESH/D004009 MESH LOOM
http://purl.bioontology.org/ontology/LNC/LP14990-3 LOINC LOOM
http://stirdf.jst.go.jp/id/200907002660859287 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D004009 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372873001 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU002293 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3891 OCHV LOOM
http://purl.jp/bio/4/id/200906064762157483 IOBC LOOM
http://purl.bioontology.org/ontology/NDDF/002703 NDDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.260.825.625.150.205 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.108.750.625.150.205 RH-MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4019715 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.605.084.737.625.150.205 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_4511 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_4511 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_4511 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_4511 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_4511 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_4511 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_4511 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4511 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_4511 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_4511 GENEPIO LOOM
http://purl.obolibrary.org/obo/MESH_D004009 BERO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147807 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.589.099.750.625.150.205 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.075.080.875.099.221.750.625.150.205 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0012093 OCHV LOOM
http://purl.obolibrary.org/obo/NCIT_C28986 BERO LOOM