loading...| Preferred Name |
Penicillin G Sodium |
|
| Synonyms |
Benzylpenicillin Sodium Benzylpenicillin Sodium Salt Penicillin G Sodium 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)-,(2S-(2alpha,5alpha,6beta))-, Monosodium Salt PENICILLIN G SODIUM Sugracillin Sodium Salt Novocillin Penicillin Penilaryn Veticillin |
|
| Definitions |
The sodium salt form of benzylpenicillin, a semi-synthetic, broad-spectrum penicillin antibiotic with bactericidal activity. Benzylpenicillin sodium binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28865 |
|
| CAS_Registry |
69-57-8 |
|
| CHEBI_ID |
CHEBI:51765 |
|
| Chemical_Formula |
C16H17N2O4S.Na |
|
| code |
C28865 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
The sodium salt form of benzylpenicillin, a semi-synthetic, broad-spectrum penicillin antibiotic with bactericidal activity. Benzylpenicillin sodium binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. |
|
| FDA_UNII_Code |
YS5LY7JF4N |
|
| FULL_SYN |
Benzylpenicillin Sodium Benzylpenicillin Sodium Salt Penicillin G Sodium 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)-,(2S-(2alpha,5alpha,6beta))-, Monosodium Salt PENICILLIN G SODIUM Sugracillin Sodium Salt Novocillin Penicillin Penilaryn Veticillin |
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Penicillin G Sodium |
|
| Legacy Concept Name |
Benzylpenicillin_Sodium |
|
| NSC Number |
402815 |
|
| Preferred_Name |
Penicillin G Sodium |
|
| prefixIRI |
Thesaurus:C28865 |
|
| Semantic_Type |
Pharmacologic Substance Antibiotic |
|
| UMLS_CUI |
C0037540 |
|
| subClassOf |