National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Anthralin

Synonyms

1,8-Dihydroxy-9(10H)-anthracenone

ANTHRALIN

Anthralin

Definitions

A natural anthraquinone derivative, anti-psoriatic and anti-inflammatory Anthralin (dithranol) controls skin growth by reducing DNA synthesis and mitotic activity in the hyperplastic epidermis, restoring a normal rate of cell proliferation and keratinization. Used topically in the treatment of psoriasis, dermatoses, and alopecia areata, it is also used in biomedical research due to its effect on EGFR autophosphorylation. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28827

CAS_Registry

1143-38-0

480-22-8

CHEBI_ID

CHEBI:37510

CHEBI:2756

Chemical_Formula

C14H10O3

code

C28827

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A natural anthraquinone derivative, anti-psoriatic and anti-inflammatory Anthralin (dithranol) controls skin growth by reducing DNA synthesis and mitotic activity in the hyperplastic epidermis, restoring a normal rate of cell proliferation and keratinization. Used topically in the treatment of psoriasis, dermatoses, and alopecia areata, it is also used in biomedical research due to its effect on EGFR autophosphorylation. (NCI04)

FDA_UNII_Code

U8CJK0JH5M

FULL_SYN

1,8-Dihydroxy-9(10H)-anthracenone

ANTHRALIN

Anthralin

label

Anthralin

Legacy Concept Name

Anthralin

NSC Number

43970

629313

Preferred_Name

Anthralin

prefixIRI

Thesaurus:C28827

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0003166

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29708

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