loading...| Preferred Name |
Hormone Replacement Therapy |
|
| Synonyms |
Hormone Replacement Rx menopausal hormone therapy Hormone Replacement Therapy hormone replacement therapy hormone_replacement_therapy_type hormone replacement therapy type HRT |
|
| Definitions |
Treatment with estrogens or estrogen/progesterone after menopause or ovariectomy to prevent pathological effects of decreased estrogen production. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C15599 |
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| ALT_DEFINITION |
Hormones (estrogen, progesterone, or both) given to women after menopause to replace the hormones no longer produced by the ovaries. |
|
| code |
C15599 |
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| Concept_In_Subset | ||
| Contributing_Source |
GDC |
|
| DEFINITION |
Treatment with estrogens or estrogen/progesterone after menopause or ovariectomy to prevent pathological effects of decreased estrogen production. |
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| DesignNote |
In women, treatment with sex hormones is indicated for a number of reasons, including menopause, partial or full hysterectomy, or amenorrhea. NHLBI of NIH stopped early a major clinical trial of the risks and benefits of combined estrogen and progestin in healthy menopausal women due to an increased risk of invasive breast cancer and lack of overall benefit. Though with fewer cases of hip fractures and colon cancer, combined estrogen and progestin leads to an increased risk of invasive breast cancer, coronary heart disease, stroke, and pulmonary embolism in healthy menopausal women on estrogen plus progestin compared to those taking placebo pills. However, a separate study of estrogen alone in women who had a hysterectomy before receiving therapy continues unchanged because, at this point, the balance of risks and benefits of estrogen alone is still uncertain. (http://www.nhlbi.nih.gov/new/press/02-07-09.htm and NCI) |
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| FULL_SYN |
Hormone Replacement Rx menopausal hormone therapy Hormone Replacement Therapy hormone replacement therapy hormone_replacement_therapy_type hormone replacement therapy type HRT |
|
| Has_GDC_Value |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17998 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179434 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43234 |
|
| label |
Hormone Replacement Therapy |
|
| Legacy Concept Name |
Hormone_Replacement_Therapy |
|
| Preferred_Name |
Hormone Replacement Therapy |
|
| prefixIRI |
Thesaurus:C15599 |
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| Semantic_Type |
Therapeutic or Preventive Procedure |
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| UMLS_CUI |
C0282402 |
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| subClassOf |