Preferred Name |
Cisapride |
|
Synonyms |
cis-4-Amino-5-Chloro-N-(1-(3- (p-fluorophenoxy)propyl)-3-methoxy-4- piperidyl)-o-Anisamide CISAPRIDE Cisapride Propulsid |
|
Definitions |
A substituted piperidinyl benzamide prokinetic agent. Cisapride facilitates release of acetylcholine from the myenteric plexus, resulting in increased gastrointestinal motility. In addition, cisapride has been found to act as a serotonin agonist, stimulating type 4 receptors, and a serotonin 5-HT3 receptor antagonist. (NCI) |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1210 |
|
CAS_Registry |
81098-60-4 |
|
CHEBI_ID |
CHEBI:3720 |
|
Chemical_Formula |
C23H29ClFN3O4 |
|
code |
C1210 |
|
Concept_In_Subset | ||
Contributing_Source |
FDA |
|
DEFINITION |
A substituted piperidinyl benzamide prokinetic agent. Cisapride facilitates release of acetylcholine from the myenteric plexus, resulting in increased gastrointestinal motility. In addition, cisapride has been found to act as a serotonin agonist, stimulating type 4 receptors, and a serotonin 5-HT3 receptor antagonist. (NCI) |
|
FDA_UNII_Code |
UVL329170W |
|
FULL_SYN |
cis-4-Amino-5-Chloro-N-(1-(3- (p-fluorophenoxy)propyl)-3-methoxy-4- piperidyl)-o-Anisamide CISAPRIDE Cisapride Propulsid |
|
label |
Cisapride |
|
Legacy Concept Name |
Cisapride |
|
NCI_Drug_Dictionary_ID |
41689 |
|
PDQ_Closed_Trial_Search_ID |
41689 |
|
PDQ_Open_Trial_Search_ID |
41689 |
|
Preferred_Name |
Cisapride |
|
prefixIRI |
Thesaurus:C1210 |
|
Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
UMLS_CUI |
C0072916 |
|
subClassOf |