National Cancer Institute Thesaurus

Last uploaded: December 30, 2019
Preferred Name

Cisapride

Synonyms

cis-4-Amino-5-Chloro-N-(1-(3- (p-fluorophenoxy)propyl)-3-methoxy-4- piperidyl)-o-Anisamide

Cisapride

Propulsid

CISAPRIDE

Definitions

A substituted piperidinyl benzamide prokinetic agent. Cisapride facilitates release of acetylcholine from the myenteric plexus, resulting in increased gastrointestinal motility. In addition, cisapride has been found to act as a serotonin agonist, stimulating type 4 receptors, and a serotonin 5-HT3 receptor antagonist. (NCI)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1210

CAS_Registry

81098-60-4

CHEBI_ID

CHEBI:3720

Chemical_Formula

C23H29ClFN3O4

code

C1210

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A substituted piperidinyl benzamide prokinetic agent. Cisapride facilitates release of acetylcholine from the myenteric plexus, resulting in increased gastrointestinal motility. In addition, cisapride has been found to act as a serotonin agonist, stimulating type 4 receptors, and a serotonin 5-HT3 receptor antagonist. (NCI)

FDA_UNII_Code

UVL329170W

FULL_SYN

cis-4-Amino-5-Chloro-N-(1-(3- (p-fluorophenoxy)propyl)-3-methoxy-4- piperidyl)-o-Anisamide

Cisapride

Propulsid

CISAPRIDE

label

Cisapride

Legacy_Concept_Name

Cisapride

PDQ_Closed_Trial_Search_ID

41689

PDQ_Open_Trial_Search_ID

41689

Preferred_Name

Cisapride

prefixIRI

ncit:C1210

Semantic_Type

Pharmacologic Substance

Organic Chemical

UMLS_CUI

C0072916

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C267

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http://www.drugbank.ca/drugs/DB00604 FTC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU012783 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.621.135 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/D020117 MESH LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000041689 PDQ LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0072916 OCHV LOOM
http://purl.bioontology.org/ontology/CSP/4001-0030 CRISP LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.223.100.050.500.700 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#14735 OCHV LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148339 NDFRT LOOM
http://purl.bioontology.org/ontology/LNC/LP21146-3 LOINC LOOM
http://purl.obolibrary.org/obo/CHEBI_3720 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_3720 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3720 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3720 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_3720 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3720 DRON LOOM
http://purl.bioontology.org/ontology/SNMI/C-84990 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.389.127.085.135 RH-MESH LOOM
http://stirdf.jst.go.jp/id/200907038303793124 IOBC LOOM
http://purl.bioontology.org/ontology/UATC/A03FA02 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.223.100.200.374 RH-MESH LOOM
http://purl.bioontology.org/ontology/RCD/dhj.. RCD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D020117 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.389.127.020.937.700 RH-MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4020825 VANDF LOOM
http://purl.bioontology.org/ontology/RXNORM/35255 RXNORM LOOM
http://www.co-ode.org/ontologies/galen#Cisapride GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.389.127.250.374 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.277.135 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.223.100.100.135 RH-MESH LOOM
http://purl.jp/bio/4/id/200906001025099160 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387164008 SNOMEDCT LOOM