National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Perforin-1
Synonyms

Lymphocyte Pore-Forming Protein

Cytolysin

P1

PFP

PRF1

Perforin-1

Definitions

Perforin-1 (555 aa, ~61 kDa) is encoded by the human PRF1 gene. This protein is involved in the mediation of cytolysis of infected cells.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97741

code

C97741

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

Perforin-1 (555 aa, ~61 kDa) is encoded by the human PRF1 gene. This protein is involved in the mediation of cytolysis of infected cells.

Display_Name

Perforin-1

FULL_SYN

Lymphocyte Pore-Forming Protein

Cytolysin

P1

PFP

PRF1

Perforin-1

label

Perforin-1

OMIM_Number

170280

Preferred_Name

Perforin-1

prefixIRI

Thesaurus:C97741

Semantic_Type

Amino Acid, Peptide, or Protein

Swiss_Prot

P14222

UMLS_CUI

C1622765

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16725

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