loading...| Preferred Name | Nucleoside Reverse Transcriptase Inhibitor | |
| Synonyms |
Nucleoside Analog Reverse Transcriptase Inhibitor Nucleoside Reverse Transcriptase Inhibitor NRTI |
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| Definitions |
A substance with a structure similar to a nucleoside molecule that is capable of occupying the active catalytic site of a reverse transcriptase resulting in inhibition of enzyme function, chain termination, and inhibition of viral replication. These compounds are converted to their active phosphorylated forms by cellular kinases. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97452 |
|
| code |
C97452 |
|
| DEFINITION |
A substance with a structure similar to a nucleoside molecule that is capable of occupying the active catalytic site of a reverse transcriptase resulting in inhibition of enzyme function, chain termination, and inhibition of viral replication. These compounds are converted to their active phosphorylated forms by cellular kinases. |
|
| FULL_SYN |
Nucleoside Analog Reverse Transcriptase Inhibitor Nucleoside Reverse Transcriptase Inhibitor NRTI |
|
| label |
Nucleoside Reverse Transcriptase Inhibitor |
|
| Preferred_Name |
Nucleoside Reverse Transcriptase Inhibitor |
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| prefixIRI |
Thesaurus:C97452 |
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| Semantic_Type |
Chemical Viewed Functionally |
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| UMLS_CUI |
C1373111 |
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| subClassOf |