loading...| Preferred Name |
Vinblastine Sulfate |
|
| Synonyms |
VINBLASTINE SULFATE vinblastine sulfate Vinblastine Sulfate VINCALEUKOBLASTINE 29060 LE 29060-LE Exal Velban Velbe Velsar |
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| Definitions |
The sulfate salt of vinblastine, a natural alkaloid isolated from the plant Catharanthus roseus (Madagascar periwinkle) with antineoplastic properties. Vinblastine disrupts microtubule formation and function during mitosis and interferes with glutamic acid metabolism. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C931 |
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| ALT_DEFINITION |
A drug used with other drugs to treat several types of cancer, including advanced Hodgkin lymphoma and advanced testicular germinal-cell cancers. It is also being studied in the treatment of other types of cancer. Velban comes from the periwinkle plant Vinca rosea Linn. It blocks cell growth by stopping cell division and may kill cancer cells. It is a type of vinca alkaloid and a type of antimitotic agent. |
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| CAS_Registry |
143-67-9 |
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| CHEBI_ID |
CHEBI:9984 |
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| Chemical_Formula |
C46H58N4O9.H2O4S |
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| code |
C931 |
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 |
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| Contributing_Source |
CTRP FDA GDC |
|
| DEFINITION |
The sulfate salt of vinblastine, a natural alkaloid isolated from the plant Catharanthus roseus (Madagascar periwinkle) with antineoplastic properties. Vinblastine disrupts microtubule formation and function during mitosis and interferes with glutamic acid metabolism. (NCI04) |
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| Display_Name |
Vinblastine Sulfate |
|
| FDA_UNII_Code |
N00W22YO2B |
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| FULL_SYN |
VINBLASTINE SULFATE vinblastine sulfate Vinblastine Sulfate VINCALEUKOBLASTINE 29060 LE 29060-LE Exal Velban Velbe Velsar |
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| Has_Free_Acid_Or_Base_Form | ||
| Has_Target | ||
| Is_Value_For_GDC_Property | ||
| label |
Vinblastine Sulfate |
|
| Legacy Concept Name |
Vinblastine_Sulfate |
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| Maps_To |
Vinblastine Sulfate |
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| NCI_Drug_Dictionary_ID |
688303 |
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| NSC Number |
49842 |
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| PDQ_Closed_Trial_Search_ID |
688303 |
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| PDQ_Open_Trial_Search_ID |
688303 |
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| Preferred_Name |
Vinblastine Sulfate |
|
| prefixIRI |
Thesaurus:C931 |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
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| UMLS_CUI |
C0042671 |
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| subClassOf |