Preferred Name |
Coagulation Factor V |
|
Synonyms |
Proaccelerin, Labile Factor Coagulation Factor V Activated Protein C Cofactor Labile Factor F5 Factor V |
|
Definitions |
Coagulation factor V (2224 aa, ~252 kDa) is encoded by the human F5 gene. This protein plays a role in the coagulation cascade. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91335 |
|
code |
C91335 |
|
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
Contributing_Source |
CTRP |
|
DEFINITION |
Coagulation factor V (2224 aa, ~252 kDa) is encoded by the human F5 gene. This protein plays a role in the coagulation cascade. |
|
DesignNote |
Coagulation factor V has no activity until it is cleaved by thrombin into two chains, called coagulation factor V heavy chain and coagulation factor V light chain. The two chains are non-covalently bound in a complex, factor Va, which is a cofactor that enhances the enzymatic activity of coagulation factor Xa. |
|
Display_Name |
Coagulation Factor V |
|
FULL_SYN |
Proaccelerin, Labile Factor Coagulation Factor V Activated Protein C Cofactor Labile Factor F5 Factor V |
|
label |
Coagulation Factor V |
|
OMIM_Number |
612309 |
|
Preferred_Name |
Coagulation Factor V |
|
prefixIRI |
Thesaurus:C91335 |
|
Semantic_Type |
Amino Acid, Peptide, or Protein |
|
Swiss_Prot |
P12259 |
|
UMLS_CUI |
C0015498 |
|
subClassOf |