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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Coagulation Factor V | |
| Synonyms |
Proaccelerin, Labile Factor Coagulation Factor V Activated Protein C Cofactor Labile Factor F5 Factor V |
|
| Definitions |
Coagulation factor V (2224 aa, ~252 kDa) is encoded by the human F5 gene. This protein plays a role in the coagulation cascade. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91335 |
|
| code |
C91335
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
| Contributing_Source |
CTRP
|
|
| DEFINITION |
Coagulation factor V (2224 aa, ~252 kDa) is encoded by the human F5 gene. This protein plays a role in the coagulation cascade.
|
|
| DesignNote |
Coagulation factor V has no activity until it is cleaved by thrombin into two chains, called coagulation factor V heavy chain and coagulation factor V light chain. The two chains are non-covalently bound in a complex, factor Va, which is a cofactor that enhances the enzymatic activity of coagulation factor Xa.
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|
| Display_Name |
Coagulation Factor V
|
|
| FULL_SYN |
Proaccelerin, Labile Factor Coagulation Factor V Activated Protein C Cofactor Labile Factor F5 Factor V
|
|
| label |
Coagulation Factor V
|
|
| OMIM_Number |
612309
|
|
| Preferred_Name |
Coagulation Factor V
|
|
| prefixIRI |
Thesaurus:C91335
|
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
|
|
| Swiss_Prot |
P12259
|
|
| UMLS_CUI |
C0015498
|
|
| subClassOf |
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