National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Coagulation Factor V

Synonyms

Proaccelerin, Labile Factor

Coagulation Factor V

Activated Protein C Cofactor

Labile Factor

F5

Factor V

Definitions

Coagulation factor V (2224 aa, ~252 kDa) is encoded by the human F5 gene. This protein plays a role in the coagulation cascade.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91335

code

C91335

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

Coagulation factor V (2224 aa, ~252 kDa) is encoded by the human F5 gene. This protein plays a role in the coagulation cascade.

DesignNote

Coagulation factor V has no activity until it is cleaved by thrombin into two chains, called coagulation factor V heavy chain and coagulation factor V light chain. The two chains are non-covalently bound in a complex, factor Va, which is a cofactor that enhances the enzymatic activity of coagulation factor Xa.

Display_Name

Coagulation Factor V

FULL_SYN

Proaccelerin, Labile Factor

Coagulation Factor V

Activated Protein C Cofactor

Labile Factor

F5

Factor V

label

Coagulation Factor V

OMIM_Number

612309

Preferred_Name

Coagulation Factor V

prefixIRI

Thesaurus:C91335

Semantic_Type

Amino Acid, Peptide, or Protein

Swiss_Prot

P12259

UMLS_CUI

C0015498

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16354

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