loading...| Preferred Name | Somatropin | |
| Synonyms |
Somatotropic Hormone Recombinant Human Growth Hormone Growth Hormone, Human Recombinant GH Recombinant Somatotropin Asellacrin Crescormon Genotropin Omnitrope SOMATROPIN Somatropin rhGH |
|
| Definitions |
A recombinant form of endogenous human growth hormone (GH), a polypeptide produced by the anterior lobe of the human pituitary gland. GH exhibits growth-promoting effects and metabolic effects on carbohydrate, fat, protein and bone metabolism. GH stimulates protein synthesis and the uptake of amino acids into cells, and induces lipolysis in adipose tissues. The secretion of GH increases with sexual maturation and then declines steadily. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C837 |
|
| CAS_Registry |
12629-01-5 |
|
| code |
C837 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA |
|
| DEFINITION |
A recombinant form of endogenous human growth hormone (GH), a polypeptide produced by the anterior lobe of the human pituitary gland. GH exhibits growth-promoting effects and metabolic effects on carbohydrate, fat, protein and bone metabolism. GH stimulates protein synthesis and the uptake of amino acids into cells, and induces lipolysis in adipose tissues. The secretion of GH increases with sexual maturation and then declines steadily. |
|
| Display_Name |
Somatropin |
|
| FDA_UNII_Code |
NQX9KB6PCL |
|
| FULL_SYN |
Somatotropic Hormone Recombinant Human Growth Hormone Growth Hormone, Human Recombinant GH Recombinant Somatotropin Asellacrin Crescormon Genotropin Omnitrope SOMATROPIN Somatropin rhGH |
|
| label |
Somatropin |
|
| Legacy Concept Name |
Therapeutic_Growth_Hormone |
|
| NCI_Drug_Dictionary_ID |
456264 |
|
| NSC Number |
64948 |
|
| PDQ_Closed_Trial_Search_ID |
456264 |
|
| PDQ_Open_Trial_Search_ID |
456264 |
|
| Preferred_Name |
Somatropin |
|
| prefixIRI |
Thesaurus:C837 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Pharmacologic Substance |
|
| UMLS_CUI |
C0169964 |
|
| subClassOf |