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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Id | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80523
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80523
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|---|---|
| Preferred Name | Gamma-Aminobutyric Acid |
| Definitions |
A naturally occurring neurotransmitter with central nervous system (CNS) inhibitory activity. Gamma-aminobutyric acid (GABA), converted from the principal excitatory neurotransmitter glutamate in the brain, plays a role in regulating neuronal excitability by binding to its receptors, GABA-A and GABA-B, and thereby causing ion channel opening, hyperpolarization and eventually inhibition of neurotransmission.
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| Synonyms |
4-Aminobutanoic Acid
Gamma-Aminobutyric Acid
Piperidic Acid
.GAMMA.-AMINOBUTYRIC ACID
GABA
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Gamma-Aminobutyric Acid
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|---|---|
| Legacy Concept Name |
Gamma-Aminobutyric_Acid
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| CHEBI_ID |
CHEBI:16865
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| Preferred_Name |
Gamma-Aminobutyric Acid
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| Semantic_Type |
Pharmacologic Substance
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| prefixIRI |
Thesaurus:C80523
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| DEFINITION |
A naturally occurring neurotransmitter with central nervous system (CNS) inhibitory activity. Gamma-aminobutyric acid (GABA), converted from the principal excitatory neurotransmitter glutamate in the brain, plays a role in regulating neuronal excitability by binding to its receptors, GABA-A and GABA-B, and thereby causing ion channel opening, hyperpolarization and eventually inhibition of neurotransmission.
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| UMLS_CUI |
C0016904
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| code |
C80523
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| Chemical_Formula |
C4H9NO2
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| subClassOf | |
| type | |
| CAS_Registry |
56-12-2
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| FULL_SYN |
4-Aminobutanoic Acid
Gamma-Aminobutyric Acid
Piperidic Acid
.GAMMA.-AMINOBUTYRIC ACID
GABA
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| FDA_UNII_Code |
2ACZ6IPC6I
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| Contributing_Source |
FDA
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| Concept_In_Subset |
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