Preferred Name |
Thrombotic Thrombocytopenic Purpura |
|
Synonyms |
Moschowitz Disease Thrombotic thrombocytopenic purpura Thrombotic Thrombocytopenic Purpura TTP |
|
Definitions |
A coagulation disorder characterized by extensive formation of thrombi in small blood vessels throughout the body due to low levels of ADAMTS13 protein, and resulting in consumption of circulating platelets, which is characterized by thrombocytopenia, anemia, neurologic changes, and sometimes fever and renal dysfunction. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78797 |
|
ALT_DEFINITION |
A disorder characterized by the presence of microangiopathic hemolytic anemia, thrombocytopenic purpura, fever, renal abnormalities and neurological abnormalities such as seizures, hemiplegia, and visual disturbances. It is an acute or subacute condition. A coagulation disorder characterized by extensive formation of thrombi in small blood vessels throughout the body due to low levels of ADAMTS13 protein, and resulting in consumption of circulating platelets, which is characterized by thrombocytopenia, anemia, neurologic changes, and sometimes fever and renal dysfunction. |
|
code |
C78797 |
|
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123272 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C192842 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118168 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165258 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189762 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132009 |
|
Contributing_Source |
Cellosaurus CTRP GDC MedDRA NICHD |
|
DEFINITION |
A coagulation disorder characterized by extensive formation of thrombi in small blood vessels throughout the body due to low levels of ADAMTS13 protein, and resulting in consumption of circulating platelets, which is characterized by thrombocytopenia, anemia, neurologic changes, and sometimes fever and renal dysfunction. |
|
Display_Name |
Thrombotic Thrombocytopenic Purpura |
|
FULL_SYN |
Moschowitz Disease Thrombotic thrombocytopenic purpura Thrombotic Thrombocytopenic Purpura TTP |
|
Is_Value_For_GDC_Property | ||
label |
Thrombotic Thrombocytopenic Purpura |
|
Legacy Concept Name |
Thrombotic_Thrombocytopenic_Purpura |
|
Maps_To |
Thrombotic thrombocytopenic purpura HUS/TTP |
|
Preferred_Name |
Thrombotic Thrombocytopenic Purpura |
|
prefixIRI |
Thesaurus:C78797 |
|
Semantic_Type |
Disease or Syndrome |
|
UMLS_CUI |
C0034155 |
|
subClassOf |