National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Iron Overload

Synonyms

Iron Overload

iron overload

Iron overload

Definitions

Accumulation of iron in the tissues. It may be a manifestation of an inherited disorder (e.g., hemochromatosis) or acquired (in patients with repeated blood transfusions). Symptoms include hepatomegaly, arthritis, diabetes mellitus, and bronzed skin. If untreated it has a progressive course and may lead to death.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78393

ALT_DEFINITION

A disorder characterized by accumulation of iron in the tissues.

A condition in which the body takes up and stores more iron than it needs. The extra iron is stored in the liver, heart, and pancreas, which may cause liver disease, heart problems, organ failure, and cancer. It may also cause bronze skin, diabetes, pain in the joints and abdomen, tiredness, and impotence. Iron overload may be inherited, or it may be caused by blood transfusions.

Abnormally high level of iron in the tissues.

code

C78393

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118168

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189762

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118464

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537

Contributing_Source

CTRP

GDC

MedDRA

NICHD

DEFINITION

Accumulation of iron in the tissues. It may be a manifestation of an inherited disorder (e.g., hemochromatosis) or acquired (in patients with repeated blood transfusions). Symptoms include hepatomegaly, arthritis, diabetes mellitus, and bronzed skin. If untreated it has a progressive course and may lead to death.

Display_Name

Iron Overload

FULL_SYN

Iron Overload

iron overload

Iron overload

Is_Value_For_GDC_Property

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17103

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16457

label

Iron Overload

Legacy Concept Name

Iron_Overload

Maps_To

Iron Overload

Iron overload

Preferred_Name

Iron Overload

prefixIRI

Thesaurus:C78393

Semantic_Type

Finding

UMLS_CUI

C3806118

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36291

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Delete Mapping To Ontology Source
http://www.co-ode.org/ontologies/galen#IronOverload GALEN LOOM
http://purl.obolibrary.org/obo/DOID_2350 CLO LOOM
http://www.semanticweb.org/david/ontologies/2013/0/pathLex.owl#1.3.6.1.4.1.19376.1.8.2.1.2329 PATHLEX LOOM
http://purl.jp/bio/4/id/200906097762668319 IOBC LOOM
http://purl.bioontology.org/ontology/MESH/D019190 MESH LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU067439 OMIM LOOM
http://purl.bioontology.org/ontology/MEDDRA/10065973 MEDDRA LOOM
http://purl.obolibrary.org/obo/CCTO_000800 CCTOO LOOM
http://bmi.utah.edu/ontologies/hfontology/C0282193 HFO LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000436017 PDQ LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#27512 OCHV LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0282193 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C18.452.565.500 RH-MESH LOOM
http://www.owl-ontologies.com/NPOntology.owl#DOID_2350 NATPRO LOOM
http://radlex.org/RID/RID5203 RADLEX LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D019190 RH-MESH LOOM
http://purl.bioontology.org/ontology/RCD/X40Yc RCD LOOM
http://www.phoc.org.cn/pmo/class/PMO_00038533 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/NCIT_C78393 BERO LOOM
http://purl.obolibrary.org/obo/NCIT_C78393 SCDO LOOM
http://purl.obolibrary.org/obo/OMIT_0019266 OMIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/ctcae5.owl#C55993 CTCAE LOOM
http://id.nlm.nih.gov/mesh/D019190 MDM LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/60737008 SNOMEDCT LOOM