National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
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Id http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78393
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78393
Preferred Name

Iron Overload
Definitions
Accumulation of iron in the tissues. It may be a manifestation of an inherited disorder (e.g., hemochromatosis) or acquired (in patients with repeated blood transfusions). Symptoms include hepatomegaly, arthritis, diabetes mellitus, and bronzed skin. If untreated it has a progressive course and may lead to death.
Synonyms
Iron Overload
iron overload
Iron overload
Type http://www.w3.org/2002/07/owl#Class

All Properties

label
Iron Overload
Maps_To
Iron Overload
Iron overload
Legacy Concept Name
Iron_Overload
Is_Value_For_GDC_Property
Preferred_Name
Iron Overload
Display_Name
Iron Overload
Semantic_Type
Finding
prefixIRI
Thesaurus:C78393
DEFINITION
Accumulation of iron in the tissues. It may be a manifestation of an inherited disorder (e.g., hemochromatosis) or acquired (in patients with repeated blood transfusions). Symptoms include hepatomegaly, arthritis, diabetes mellitus, and bronzed skin. If untreated it has a progressive course and may lead to death.
UMLS_CUI
C3806118
code
C78393
subClassOf
type
FULL_SYN
Iron Overload
iron overload
Iron overload
ALT_DEFINITION
A disorder characterized by accumulation of iron in the tissues.
A condition in which the body takes up and stores more iron than it needs. The extra iron is stored in the liver, heart, and pancreas, which may cause liver disease, heart problems, organ failure, and cancer. It may also cause bronze skin, diabetes, pain in the joints and abdomen, tiredness, and impotence. Iron overload may be inherited, or it may be caused by blood transfusions.
Abnormally high level of iron in the tissues.
Contributing_Source
CTRP
GDC
MedDRA
NICHD
Concept_In_Subset
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