National Cancer Institute Thesaurus

Last uploaded: February 23, 2024

Preferred Name	Saxagliptin Anhydrous
Synonyms	Saxagliptin Anhydrous SAXAGLIPTIN ANHYDROUS
Definitions	The anhydrous form of saxagliptin, a potent, selective and competitive, cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Saxagliptin is metabolized into an, although less potent, active mono-hydroxy metabolite.
ID	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75984
CAS_Registry	361442-04-8
Chemical_Formula	C18H25N3O2
code	C75984
Concept_In_Subset	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923
Contributing_Source	FDA
DEFINITION	The anhydrous form of saxagliptin, a potent, selective and competitive, cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Saxagliptin is metabolized into an, although less potent, active mono-hydroxy metabolite.
FDA_UNII_Code	8I7IO46IVQ
FULL_SYN	Saxagliptin Anhydrous SAXAGLIPTIN ANHYDROUS
label	Saxagliptin Anhydrous
Legacy Concept Name	Saxagliptin_Anhydrous
Preferred_Name	Saxagliptin Anhydrous
prefixIRI	Thesaurus:C75984
Semantic_Type	Pharmacologic Substance
UMLS_CUI	C2699273
subClassOf	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C98086

Delete	Subject	Author	Type	Created
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Delete	Mapping To	Ontology	Source
	http://purl.obolibrary.org/obo/NCIT_C75984	BERO	LOOM
	http://purl.bioontology.org/ontology/RXNORM/1546030	RXNORM	LOOM