National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Id http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C73100
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C73100
Preferred Name

Alosetron

Definitions
A potent and selective 5-HT3 receptor antagonist. Alosetron blocks the actions of serotonin at 5-HT3 sites in the peripheral nervous system, particularly on enteric and nociceptive sensory neurons, thereby affecting the regulation of visceral pain, decreasing gastrointestinal contraction and motility, and decreasing gastrointestinal secretions. This agent is used to treat diarrhea-predominant irritable bowel syndrome in women.
Synonyms
ALOSETRON
Alosetron
GR 68755
Type http://www.w3.org/2002/07/owl#Class
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