National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Diffuse Astrocytoma
Synonyms

WHO Grade 2 Astrocytoma

ASTROCYTOMA, DIFFUSE, MALIGNANT

Grade II Astrocytic Neoplasm

Diffuse astrocytoma

Grade 2 Astrocytoma

Low-grade astrocytoma, NOS

Grade 2 Astrocytic Neoplasm

Grade II Astrocytoma

Grade 2 Astrocytic Tumor

WHO Grade II Astrocytoma

Grade II Astrocytic Tumor

Astrocytoma, Diffuse

Diffuse Astrocytoma

Definitions

A low-grade (WHO grade 2) astrocytic neoplasm. It is characterized by diffuse infiltration of neighboring central nervous system structures. These lesions typically affect young adults and have a tendency for progression to anaplastic astrocytoma and glioblastoma. Based on the IDH genes mutation status, diffuse astrocytomas are classified as IDH-mutant, IDH-wildtype, and not otherwise specified.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7173

ALT_DEFINITION

A malignant astrocytic neoplasm characterized by a high degree of cellular differentiation, slow growth, and diffuse infiltration of neighboring brain structures.

code

C7173

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C77526

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88025

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C103043

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126659

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102905

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537

Contributing_Source

CDISC

CTEP

GDC

DEFINITION

A low-grade (WHO grade 2) astrocytic neoplasm. It is characterized by diffuse infiltration of neighboring central nervous system structures. These lesions typically affect young adults and have a tendency for progression to anaplastic astrocytoma and glioblastoma. Based on the IDH genes mutation status, diffuse astrocytomas are classified as IDH-mutant, IDH-wildtype, and not otherwise specified.

FULL_SYN

WHO Grade 2 Astrocytoma

ASTROCYTOMA, DIFFUSE, MALIGNANT

Grade II Astrocytic Neoplasm

Diffuse astrocytoma

Grade 2 Astrocytoma

Low-grade astrocytoma, NOS

Grade 2 Astrocytic Neoplasm

Grade II Astrocytoma

Grade 2 Astrocytic Tumor

WHO Grade II Astrocytoma

Grade II Astrocytic Tumor

Astrocytoma, Diffuse

Diffuse Astrocytoma

Is_Value_For_GDC_Property

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177621

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176985

label

Diffuse Astrocytoma

Legacy Concept Name

Diffuse_Astrocytoma

Maps_To

Cystic astrocytoma

Diffuse astrocytoma

Astrocytoma, low grade

Diffuse astrocytoma, low grade

9400/3

Neoplastic_Status

Undetermined

Preferred_Name

Diffuse Astrocytoma

prefixIRI

Thesaurus:C7173

Semantic_Type

Neoplastic Process

UMLS_CUI

C0280785

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116342

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132505

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129325

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