Preferred Name | Diffuse Astrocytoma | |
Synonyms |
WHO Grade 2 Astrocytoma ASTROCYTOMA, DIFFUSE, MALIGNANT Grade II Astrocytic Neoplasm Diffuse astrocytoma Grade 2 Astrocytoma Low-grade astrocytoma, NOS Grade 2 Astrocytic Neoplasm Grade II Astrocytoma Grade 2 Astrocytic Tumor WHO Grade II Astrocytoma Grade II Astrocytic Tumor Astrocytoma, Diffuse Diffuse Astrocytoma |
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Definitions |
A low-grade (WHO grade 2) astrocytic neoplasm. It is characterized by diffuse infiltration of neighboring central nervous system structures. These lesions typically affect young adults and have a tendency for progression to anaplastic astrocytoma and glioblastoma. Based on the IDH genes mutation status, diffuse astrocytomas are classified as IDH-mutant, IDH-wildtype, and not otherwise specified. |
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ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7173 |
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ALT_DEFINITION |
A malignant astrocytic neoplasm characterized by a high degree of cellular differentiation, slow growth, and diffuse infiltration of neighboring brain structures. |
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code |
C7173 |
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Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C77526 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88025 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C103043 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126659 |
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Contributing_Source |
CDISC CTEP GDC |
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DEFINITION |
A low-grade (WHO grade 2) astrocytic neoplasm. It is characterized by diffuse infiltration of neighboring central nervous system structures. These lesions typically affect young adults and have a tendency for progression to anaplastic astrocytoma and glioblastoma. Based on the IDH genes mutation status, diffuse astrocytomas are classified as IDH-mutant, IDH-wildtype, and not otherwise specified. |
|
FULL_SYN |
WHO Grade 2 Astrocytoma ASTROCYTOMA, DIFFUSE, MALIGNANT Grade II Astrocytic Neoplasm Diffuse astrocytoma Grade 2 Astrocytoma Low-grade astrocytoma, NOS Grade 2 Astrocytic Neoplasm Grade II Astrocytoma Grade 2 Astrocytic Tumor WHO Grade II Astrocytoma Grade II Astrocytic Tumor Astrocytoma, Diffuse Diffuse Astrocytoma |
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Is_Value_For_GDC_Property | ||
label |
Diffuse Astrocytoma |
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Legacy Concept Name |
Diffuse_Astrocytoma |
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Maps_To |
Cystic astrocytoma Diffuse astrocytoma Astrocytoma, low grade Diffuse astrocytoma, low grade 9400/3 |
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Neoplastic_Status |
Undetermined |
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Preferred_Name |
Diffuse Astrocytoma |
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prefixIRI |
Thesaurus:C7173 |
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Semantic_Type |
Neoplastic Process |
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UMLS_CUI |
C0280785 |
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subClassOf |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116342 |