National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Mitogen-Activated Protein Kinase Kinase Inhibitor
Synonyms

MKK Inhibitor

MEK Inhibitor

Mitogen-Activated Protein Kinase Kinase Inhibitor

MAP2K Inhibitor

MAPK/ERK Kinase Inhibitor

MAPKK Inhibitor

Definitions

Any substance that inhibits mitogen-activated protein kinase kinase (MEK), an enzyme that catalyzes the addition of a phosphate group to a mitogen-activated protein kinase. Inhibition of mitogen-activated protein kinase kinase results in the inhibition of cell proliferation.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C69145

code

C69145

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

Any substance that inhibits mitogen-activated protein kinase kinase (MEK), an enzyme that catalyzes the addition of a phosphate group to a mitogen-activated protein kinase. Inhibition of mitogen-activated protein kinase kinase results in the inhibition of cell proliferation.

Display_Name

Mitogen-Activated Protein Kinase Kinase Inhibitor

FULL_SYN

MKK Inhibitor

MEK Inhibitor

Mitogen-Activated Protein Kinase Kinase Inhibitor

MAP2K Inhibitor

MAPK/ERK Kinase Inhibitor

MAPKK Inhibitor

label

Mitogen-Activated Protein Kinase Kinase Inhibitor

Legacy Concept Name

Mitogen-Activated_Protein_Kinase_Kinase_Inhibitor

Preferred_Name

Mitogen-Activated Protein Kinase Kinase Inhibitor

prefixIRI

Thesaurus:C69145

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C2347168

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C163758

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1404

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