loading...| Preferred Name | Angiotensin II Receptor Antagonist | |
| Synonyms |
Angiotensin II receptor blocker (ARB) medication Angiotensin II Receptor Blocker Angiotensin II Receptor Antagonist Angiotensin II Receptor Antagonists Angiotensin Receptor Blockers ARB |
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| Definitions |
A class of agents that act by selectively inhibiting angiotensin II receptor activation in the renin-angiotensin-aldosterone system. Angiotensin II receptor antagonists bind to and block the activation of angiotensin II type 1 (AT1) receptors, thereby reducing production and secretion of aldosterone, amongst other actions. The combined effects result in reduction of blood pressure. Although this class of agents is also used in diabetic nephropathy (kidney damage due to diabetes) and congestive heart failure, it is primarily used for the treatment of hypertension in cases where the patient is intolerant of ACE inhibitor therapy. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66930 |
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| ALT_DEFINITION |
An angiotensin receptor blocker (ARB) medication, a class of agents that act by selectively inhibiting angiotensin II receptor activation in the renin-angiotensin-aldosterone system. Angiotensin II receptor antagonists bind to and block the activation of angiotensin II type 1 (AT1) receptors, thereby reducing production and secretion of aldosterone, among other actions. The combined effects result in reduction of blood pressure. It is primarily used for the treatment of hypertension or HF. A pharmaceutical agent that selectively inhibits angiotensin II receptor activation in the renin-angiotensin-aldosterone system reducing production and secretion of aldosterone, amongst other actions. The combined effects result in reduction of blood pressure. It is primarily used for the reduction of proteinuria and the treatment of hypertension in cases where the patient is intolerant of ACE inhibitor therapy. |
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| code |
C66930 |
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191670 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118468 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191200 |
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| Contributing_Source |
ACC/AHA NICHD |
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| DEFINITION |
A class of agents that act by selectively inhibiting angiotensin II receptor activation in the renin-angiotensin-aldosterone system. Angiotensin II receptor antagonists bind to and block the activation of angiotensin II type 1 (AT1) receptors, thereby reducing production and secretion of aldosterone, amongst other actions. The combined effects result in reduction of blood pressure. Although this class of agents is also used in diabetic nephropathy (kidney damage due to diabetes) and congestive heart failure, it is primarily used for the treatment of hypertension in cases where the patient is intolerant of ACE inhibitor therapy. |
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| FULL_SYN |
Angiotensin II receptor blocker (ARB) medication Angiotensin II Receptor Blocker Angiotensin II Receptor Antagonist Angiotensin II Receptor Antagonists Angiotensin Receptor Blockers ARB |
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| Has_ACC-AHA_SARS2_Authorized_Value |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17998 |
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| label |
Angiotensin II Receptor Antagonist |
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| Legacy Concept Name |
Angiotensin_II_Receptor_Antagonist |
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| Preferred_Name |
Angiotensin II Receptor Antagonist |
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| prefixIRI |
Thesaurus:C66930 |
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| Semantic_Type |
Chemical Viewed Functionally |
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| UMLS_CUI |
C0521942 |
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| subClassOf |