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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Id | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66486
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66486
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|---|---|
| Preferred Name | Propiomazine |
| Definitions |
A phenothiazine derivative and atypical antipsychotic agent with sedative, antiemetic and antipsychotic activities. Propiomazine binds to a variety of receptors, including alpha1, dopamine, histamine H1, muscarinic, and serotonin type 2 (5-HT2) receptors. Propiomazine exerts its antiemetic and sedative effects through antagonism at histamine H1 receptors; Its antipsychotic effect is attributed to antagonistic activities at dopamine and 5-HT2 receptors.
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| Synonyms |
PROPIOMAZINE
Propiomazine
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Propiomazine
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|---|---|
| Legacy Concept Name |
Propiomazine
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| CHEBI_ID |
CHEBI:8491
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| Preferred_Name |
Propiomazine
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| Semantic_Type |
Pharmacologic Substance
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| prefixIRI |
Thesaurus:C66486
|
| DEFINITION |
A phenothiazine derivative and atypical antipsychotic agent with sedative, antiemetic and antipsychotic activities. Propiomazine binds to a variety of receptors, including alpha1, dopamine, histamine H1, muscarinic, and serotonin type 2 (5-HT2) receptors. Propiomazine exerts its antiemetic and sedative effects through antagonism at histamine H1 receptors; Its antipsychotic effect is attributed to antagonistic activities at dopamine and 5-HT2 receptors.
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| UMLS_CUI |
C0033473
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| code |
C66486
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| Chemical_Formula |
C20H24N2OS
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| subClassOf | |
| type | |
| CAS_Registry |
362-29-8
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| FULL_SYN |
PROPIOMAZINE
Propiomazine
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| FDA_UNII_Code |
242Z0PM79Y
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| Contributing_Source |
FDA
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| Concept_In_Subset | |
| Has_Salt_Form |
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