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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Id | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66118
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66118
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|---|---|
| Preferred Name | Levomepromazine |
| Definitions |
A phenothiazine and typical antipsychotic agent, with sedative/hypnotic, anxiolytic, antiemetic, analgesic and antipsychotic activities. Although the exact mechanism of action of levomepromazine is not fully known, upon administration, this agent appears to act as an antagonist for a variety of receptors in the central nervous system (CNS), including adrenergic, dopamine, histamine, cholinergic and serotonin (5-hydroxytryptamine; 5-HT) receptors. Blocking these receptors results in levomepromazine's pharmacologic effects.
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| Synonyms |
Methotrimeprazine
(-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazine
Levomepromazine
LEVOMEPROMAZINE
Arc-VI-C-5
Bayer 1213
Levoprome
Neozine
Nirvan
Nozinan
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Levomepromazine
|
|---|---|
| Legacy Concept Name |
Methotrimeprazine
|
| CHEBI_ID |
CHEBI:6838
|
| Preferred_Name |
Levomepromazine
|
| Semantic_Type |
Pharmacologic Substance
|
| prefixIRI |
Thesaurus:C66118
|
| DEFINITION |
A phenothiazine and typical antipsychotic agent, with sedative/hypnotic, anxiolytic, antiemetic, analgesic and antipsychotic activities. Although the exact mechanism of action of levomepromazine is not fully known, upon administration, this agent appears to act as an antagonist for a variety of receptors in the central nervous system (CNS), including adrenergic, dopamine, histamine, cholinergic and serotonin (5-hydroxytryptamine; 5-HT) receptors. Blocking these receptors results in levomepromazine's pharmacologic effects.
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| UMLS_CUI |
C0025678
|
| code |
C66118
|
| Chemical_Formula |
C19H24N2OS
|
| subClassOf | |
| type | |
| CAS_Registry |
60-99-1
|
| FULL_SYN |
Methotrimeprazine
(-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazine
Levomepromazine
LEVOMEPROMAZINE
Arc-VI-C-5
Bayer 1213
Levoprome
Neozine
Nirvan
Nozinan
See more
See less
|
| FDA_UNII_Code |
9G0LAW7ATQ
|
| Contributing_Source |
FDA
|
| Concept_In_Subset | |
| Has_Salt_Form |
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