National Cancer Institute Thesaurus

Last uploaded: July 2, 2026
Id http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65983
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65983
Preferred Name

Isoproterenol Sulfate
Definitions
The sulfate salt form of isoproterenol, a beta-adrenergic receptor agonist with bronchodilator activity. Isoproterenol binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and inhibit the release of mediators of immediate hypersensitivity from cells, especially from mast cells.
Synonyms
Isoproterenol Sulfate
ISOPROTERENOL SULFATE
Type http://www.w3.org/2002/07/owl#Class

All Properties

label
Isoproterenol Sulfate
prefixIRI
Thesaurus:C65983
code
C65983
DEFINITION
The sulfate salt form of isoproterenol, a beta-adrenergic receptor agonist with bronchodilator activity. Isoproterenol binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and inhibit the release of mediators of immediate hypersensitivity from cells, especially from mast cells.
Legacy Concept Name
Isoproterenol_Sulfate
Contributing_Source
FDA
FULL_SYN
Isoproterenol Sulfate
ISOPROTERENOL SULFATE
Chemical_Formula
2C11H17NO3.2H2O.H2SO4
UMLS_CUI
C0282211
FDA_UNII_Code
925FX3X776
Preferred_Name
Isoproterenol Sulfate
type
subClassOf
Has_Free_Acid_Or_Base_Form
CAS_Registry
6078-56-4
Concept_In_Subset
Semantic_Type
Pharmacologic Substance
Add comment
Add proposal
Delete Subject Author Type Created
No notes to display