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National Cancer Institute Thesaurus
Preferred Name | Iron Sucrose | |
Synonyms |
Iron Sucrose Injection Iron Sucrose Ferric Hydroxide Sucrose Complex Saccharated Iron Oxide iron (III) Oxide, Saccharate Iron Sucrose for Injection Saccharated Ferric Oxide Iron sucrose Intravenous Ferric Hydroxide Saccharate Iron Saccharate Ferric Hydroxide Saccharate Injection Iron Saccharate Injection IRON SUCROSE Venofer |
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Definitions |
A sterile aqueous complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. Following intravenous administration, iron sucrose is dissociated by the reticuloendothelial system into iron and sucrose; the sucrose component is eliminated mainly by urinary excretion. Iron sucrose can be administered with or without erythropoietin to raise hemoglobin levels and may be used in cases of oral iron therapy intolerance or ineffectiveness. Hypersensitivity reactions are less common with iron sucrose compared to other parenteral iron products, such as iron dextran. |
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ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65963 |
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Accepted_Therapeutic_Use_For |
Treatment of iron deficiency for both dialysis and non-dialysis patients with kidney disease, with or without concurrent erythropoietin therapy.
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CAS_Registry |
8047-67-4
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Chemical_Formula |
C12H22O11.5Fe.2Na.8O.HO.3H2O
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code |
C65963
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Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 |
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Contributing_Source |
FDA HemOnc
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DEFINITION |
A sterile aqueous complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. Following intravenous administration, iron sucrose is dissociated by the reticuloendothelial system into iron and sucrose; the sucrose component is eliminated mainly by urinary excretion. Iron sucrose can be administered with or without erythropoietin to raise hemoglobin levels and may be used in cases of oral iron therapy intolerance or ineffectiveness. Hypersensitivity reactions are less common with iron sucrose compared to other parenteral iron products, such as iron dextran.
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FDA_UNII_Code |
FZ7NYF5N8L
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FULL_SYN |
Iron Sucrose Injection Iron Sucrose Ferric Hydroxide Sucrose Complex Saccharated Iron Oxide iron (III) Oxide, Saccharate Iron Sucrose for Injection Saccharated Ferric Oxide Iron sucrose Intravenous Ferric Hydroxide Saccharate Iron Saccharate Ferric Hydroxide Saccharate Injection Iron Saccharate Injection IRON SUCROSE Venofer
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label |
Iron Sucrose
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Legacy Concept Name |
Iron_Sucrose
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NCI_Drug_Dictionary_ID |
467930
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Preferred_Name |
Iron Sucrose
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prefixIRI |
Thesaurus:C65963
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Semantic_Type |
Pharmacologic Substance
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UMLS_CUI |
C0060241
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subClassOf |
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