National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Etilefrine
Synonyms

Apha-((ethylamino)methyl)-3-hydroxybenzenemethanol

ETILEFRINE

Etilefrine

S 40032

Definitions

An adrenergic agonist with vasoconstrictive activity. Etilefrine selectively binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This causes smooth muscle contraction and leads to a decrease in venous pooling and increase in blood pressure. This agent may also stimulate beta-1 adrenergic receptors, leading to positive chronotropic and inotropic effects.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65576

CAS_Registry

709-55-7

Chemical_Formula

C10H15NO2

code

C65576

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

An adrenergic agonist with vasoconstrictive activity. Etilefrine selectively binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This causes smooth muscle contraction and leads to a decrease in venous pooling and increase in blood pressure. This agent may also stimulate beta-1 adrenergic receptors, leading to positive chronotropic and inotropic effects.

FDA_UNII_Code

ZB6F8MY53V

FULL_SYN

Apha-((ethylamino)methyl)-3-hydroxybenzenemethanol

ETILEFRINE

Etilefrine

S 40032

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75931

label

Etilefrine

Legacy Concept Name

Etilefrine

Preferred_Name

Etilefrine

prefixIRI

Thesaurus:C65576

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0015116

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29747

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