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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Meperidine Hydrochloride | |
| Synonyms |
MEPERIDINE HYDROCHLORIDE meperidine hydrochloride Meperidine Hydrochloride Demerol Meperidine |
|
| Definitions |
The hydrochloride salt of a synthetic piperidine ester with opioid analgesic activity. Meperidine mimics the actions of endogenous neuropeptides via opioid receptors such as the mu-opioid receptor, thereby producing characteristic morphine-like effects including analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia and physical dependence. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C635 |
|
| ALT_DEFINITION |
A drug used to treat moderate to severe pain. It binds to opioid receptors in the central nervous system. Demerol is a type of analgesic agent and a type of opioid.
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|
| CAS_Registry |
50-13-5
|
|
| Chemical_Formula |
C15H21NO2.HCl
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|
| code |
C635
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156952 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159412 |
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| Contributing_Source |
CPTAC FDA
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|
| DEFINITION |
The hydrochloride salt of a synthetic piperidine ester with opioid analgesic activity. Meperidine mimics the actions of endogenous neuropeptides via opioid receptors such as the mu-opioid receptor, thereby producing characteristic morphine-like effects including analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia and physical dependence.
|
|
| FDA_UNII_Code |
N8E7F7Q170
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|
| FULL_SYN |
MEPERIDINE HYDROCHLORIDE meperidine hydrochloride Meperidine Hydrochloride Demerol Meperidine
|
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Meperidine Hydrochloride
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|
| Legacy Concept Name |
Meperidine
|
|
| NCI_Drug_Dictionary_ID |
39278
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|
| NSC Number |
400479
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|
| PDQ_Closed_Trial_Search_ID |
39278
|
|
| PDQ_Open_Trial_Search_ID |
39278
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|
| Preferred_Name |
Meperidine Hydrochloride
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|
| prefixIRI |
Thesaurus:C635
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|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
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|
| UMLS_CUI |
C0353148
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| subClassOf |
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