National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Thrombotic Microangiopathy

Synonyms

Thrombotic Microangiopathy

Thrombotic microangiopathy

TMA

Definitions

A microvascular coagulopathy that may result from systemic vascular endothelial injury triggering the development of a procoagulant state, activation of the complement cascade, and microthrombi formation. Signs may include hemolytic anemia, thrombocytopenia, hypertension and renal dysfunction.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62605

ALT_DEFINITION

The syndromes of microangiopathic hemolytic anemia, thrombocytopenia, and variable signs of organ impairment, due to platelet aggregation in the microcirculation.

code

C62605

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C193205

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132009

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C193006

Contributing_Source

NICHD

mCode

DEFINITION

A microvascular coagulopathy that may result from systemic vascular endothelial injury triggering the development of a procoagulant state, activation of the complement cascade, and microthrombi formation. Signs may include hemolytic anemia, thrombocytopenia, hypertension and renal dysfunction.

FULL_SYN

Thrombotic Microangiopathy

Thrombotic microangiopathy

TMA

label

Thrombotic Microangiopathy

Legacy Concept Name

Thrombotic_Microangiopathy

Preferred_Name

Thrombotic Microangiopathy

prefixIRI

Thesaurus:C62605

Semantic_Type

Disease or Syndrome

UMLS_CUI

C2717961

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180553

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