National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Piperacillin
Synonyms

PIPERACILLIN

Piperacillin

(2S,5R,6R)-6-((R)-2-(4-Ethyl-2,3-dioxo-1-piperazinecarboxamido)-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid Monohydrate

Definitions

A broad-spectrum semisynthetic, ampicillin-derived ureidopenicillin antibiotic. Piperacillin binds to penicillin binding proteins (PBP), the enzymes that catalyze the synthesis of peptidoglycan, a critical component of the bacterial cell wall. This blockade leads to the interruption of cell wall synthesis, consequently, leading to bacterial cell growth inhibition and cell lysis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62069

CAS_Registry

66258-76-2

Chemical_Formula

C23H27N5O7S.H2O

code

C62069

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CTRP

FDA

DEFINITION

A broad-spectrum semisynthetic, ampicillin-derived ureidopenicillin antibiotic. Piperacillin binds to penicillin binding proteins (PBP), the enzymes that catalyze the synthesis of peptidoglycan, a critical component of the bacterial cell wall. This blockade leads to the interruption of cell wall synthesis, consequently, leading to bacterial cell growth inhibition and cell lysis.

Display_Name

Piperacillin

FDA_UNII_Code

X00B0D5O0E

FULL_SYN

PIPERACILLIN

Piperacillin

(2S,5R,6R)-6-((R)-2-(4-Ethyl-2,3-dioxo-1-piperazinecarboxamido)-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid Monohydrate

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C749

label

Piperacillin

Legacy Concept Name

Piperacillin_Base

Preferred_Name

Piperacillin

prefixIRI

Thesaurus:C62069

Semantic_Type

Organic Chemical

Pharmacologic Substance

Antibiotic

UMLS_CUI

C0031955

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1558

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http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.108.750.750.050.650 RH-MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015929 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/NCIT_C62069 BERO LOOM
http://purl.bioontology.org/ontology/SNMI/C-54B30 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.589.099.750.750.050.650 RH-MESH LOOM
http://purl.jp/bio/4/id/200906085772262690 IOBC LOOM
http://purl.bioontology.org/ontology/ATC/J01CA12 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.075.080.875.099.221.750.750.050.650 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372836004 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/MESH/D010878 MESH LOOM
http://purl.bioontology.org/ontology/RCD/e37.. RCD LOOM
http://purl.obolibrary.org/obo/ARO_0000078 ARO LOOM
http://purl.obolibrary.org/obo/OMIT_0011855 OMIT LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147981 NDFRT LOOM
http://stirdf.jst.go.jp/id/200907097822249861 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU008471 LOINC LOOM
http://purl.bioontology.org/ontology/RXNORM/8339 RXNORM LOOM
http://purl.bioontology.org/ontology/VANDF/4019896 VANDF LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#9745 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.605.084.737.750.050.650 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D010878 RH-MESH LOOM
https://go.drugbank.com/drugs/DB00319 MDM LOOM
http://purl.bioontology.org/ontology/NDDF/004832 NDDF LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0031955 OCHV LOOM
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Piperacillin SEPON LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.260.825.750.050.650 RH-MESH LOOM
http://purl.obolibrary.org/obo/MESH_D010878 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_8232 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_8232 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_8232 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_8232 DOID LOOM
http://purl.obolibrary.org/obo/CHEBI_8232 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_8232 HHEAR LOOM
http://purl.obolibrary.org/obo/CHEBI_8232 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_8232 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_8232 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_8232 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_8232 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_8232 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_8232 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_8232 DRON LOOM
http://www.co-ode.org/ontologies/galen#Piperacillin GALEN LOOM
http://purl.bioontology.org/ontology/LNC/LP16256-7 LOINC LOOM