National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
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Id http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62011
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62011
Preferred Name

Bupivacaine
Definitions
An amide-type, long-acting local anesthetic. Bupivicaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation.
Synonyms
BUPIVACAINE
bupivacaine
1-Butyl-2',6'-pipecoloxylidide
Bupivacaine
AH 250
Type http://www.w3.org/2002/07/owl#Class

All Properties

label
Bupivacaine
Legacy Concept Name
Bupivacaine_Base
CHEBI_ID
CHEBI:3215
NCI_Drug_Dictionary_ID
811743
Preferred_Name
Bupivacaine
Display_Name
Bupivacaine
Semantic_Type
Organic Chemical
Pharmacologic Substance
prefixIRI
Thesaurus:C62011
DEFINITION
An amide-type, long-acting local anesthetic. Bupivicaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation.
UMLS_CUI
C0006400
code
C62011
Chemical_Formula
C18H28N2O
subClassOf
type
CAS_Registry
2180-92-9
38396-39-3
FULL_SYN
BUPIVACAINE
bupivacaine
1-Butyl-2',6'-pipecoloxylidide
Bupivacaine
AH 250
FDA_UNII_Code
Y8335394RO
ALT_DEFINITION
A drug used to relieve pain by blocking signals at nerve endings. It is being studied in the relief of pain following surgery for cancer. It is a type of local anesthetic.
Contributing_Source
CPTAC
CTRP
FDA
Concept_In_Subset
Has_Salt_Form
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