National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Amphetamine
Synonyms

AMPHETAMINE

Desoxynorephedrine

Amphetamine

Amfetamine

Benzedrine

Definitions

A synthetic substance related to natural sympathomimetic amines. Amphetamine appears to exert its central nervous system (CNS) and peripheral effects indirectly by inducing the release of biogenic amines from their storage sites in nerve terminals. This agent is a commonly abused psychostimulant drug, which may be snorted, taken orally, smoked, or injected. Amphetamine induces psychologic dependence which is manifested by elevated mood, increased wakefulness, concentration, physical performance and a feeling of well-being. With sustained use, the effects of tachycardia and enhanced alertness diminish while psychotoxic effects such as hallucinations and delusions may occur. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62006

CAS_Registry

300-62-9

60-15-1

CHEBI_ID

CHEBI:2679

Chemical_Formula

C9H13N

code

C62006

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic substance related to natural sympathomimetic amines. Amphetamine appears to exert its central nervous system (CNS) and peripheral effects indirectly by inducing the release of biogenic amines from their storage sites in nerve terminals. This agent is a commonly abused psychostimulant drug, which may be snorted, taken orally, smoked, or injected. Amphetamine induces psychologic dependence which is manifested by elevated mood, increased wakefulness, concentration, physical performance and a feeling of well-being. With sustained use, the effects of tachycardia and enhanced alertness diminish while psychotoxic effects such as hallucinations and delusions may occur. (NCI04)

FDA_UNII_Code

CK833KGX7E

FULL_SYN

AMPHETAMINE

Desoxynorephedrine

Amphetamine

Amfetamine

Benzedrine

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C77844

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61636

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28822

label

Amphetamine

Legacy Concept Name

Amphetamine_Base

NSC Number

27159

Preferred_Name

Amphetamine

prefixIRI

Thesaurus:C62006

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0002658

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47795

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http://phenomebrowser.net/ontologies/mesh/mesh.owl#D000661 RH-MESH LOOM
http://www.ustb.edu.cn/thesauri/tocr/v1/data#C571345044435366148 ACVD_ONTOLOGY LOOM
http://purl.bioontology.org/ontology/LNC/LA28413-5 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU006736 LOINC LOOM
http://www.case.edu/EpSO.owl#Amphetamine MEPO LOOM
http://purl.bioontology.org/ontology/LNC/LP18868-7 LOINC LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_5b6c1ec5_1180_4e9b_a125_e6f6e890eaa0 STO-DRAFT LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_5b6c1ec5_1180_4e9b_a125_e6f6e890eaa0 CVAO LOOM
http://purl.bioontology.org/ontology/MESH/D000661 MESH LOOM
http://purl.obolibrary.org/obo/NCIT_C62006 BERO LOOM
http://www.co-ode.org/ontologies/galen#Amphetamine GALEN LOOM
http://www.drugbank.ca/drugs/DB00182 FTC LOOM
http://purl.obolibrary.org/obo/OMIT_0002075 OMIT LOOM
http://purl.obolibrary.org/obo/CHEBI_35338 GSSO LOOM
http://purl.bioontology.org/ontology/RXNORM/725 RXNORM LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#1046 OCHV LOOM
http://doe-generated-ontology.com/OntoAD#C0002658 ONTOAD LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0002658 OCHV LOOM
http://purl.bioontology.org/ontology/NDDF/001790 NDDF LOOM
http://purl.bioontology.org/ontology/VANDF/4019611 VANDF LOOM
http://stirdf.jst.go.jp/id/200907017016120952 IOBC LOOM
https://bioportal.bioontology.org/ontologies/STMSO#Amphetamine STMSO LOOM
http://www.case.edu/EpilepsyOntology.owl#Amphetamine EPSO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0002667 OCHV LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147705 NDFRT LOOM
https://go.drugbank.com/drugs/DB00182 MDM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.471.683.152.110 RH-MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016152 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/MESH_D000661 BERO LOOM
http://purl.bioontology.org/ontology/RCD/XC0PV RCD LOOM
rgo:30747 GAMUTS LOOM
http://purl.obolibrary.org/obo/CHEBI_2679 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_2679 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_2679 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_2679 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_2679 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_2679 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_2679 GSSO LOOM
http://purl.obolibrary.org/obo/CHEBI_2679 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_2679 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_2679 ECTO LOOM
http://purl.obolibrary.org/obo/CHEBI_2679 DRON LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01932 MIO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/703842006 SNOMEDCT LOOM
http://purl.jp/bio/4/id/200906086629843017 IOBC LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Amphetamine APAONTO LOOM
http://purl.bioontology.org/ontology/CSP/2268-4026 CRISP LOOM