National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
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Preferred Name

Oleandomycin Phosphate
Synonyms

OLEANDOMYCIN PHOSPHATE

Oleandomycin Phosphate
Definitions

The phosphate salt form of oleandomycin, a macrolide antibiotic similar to erythromycin with antimicrobial activity. Oleandomycin targets and reversibly binds to the 50S subunit of bacterial ribosomes. This prevents translocation of peptidyl tRNA leading to an inhibition of protein synthesis.
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61865
CAS_Registry

7060-74-4
Chemical_Formula

C35H61NO12.H3O4P
code

C61865
Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923
Contributing_Source

FDA
DEFINITION

The phosphate salt form of oleandomycin, a macrolide antibiotic similar to erythromycin with antimicrobial activity. Oleandomycin targets and reversibly binds to the 50S subunit of bacterial ribosomes. This prevents translocation of peptidyl tRNA leading to an inhibition of protein synthesis.
FDA_UNII_Code

8681H0C27P
FULL_SYN

OLEANDOMYCIN PHOSPHATE

Oleandomycin Phosphate
Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61864
label

Oleandomycin Phosphate
Legacy Concept Name

Oleandomycin_Phosphate
Preferred_Name

Oleandomycin Phosphate
prefixIRI

Thesaurus:C61865
Semantic_Type

Pharmacologic Substance
UMLS_CUI

C0282269
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C261
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