National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Mupirocin Calcium
Synonyms

Mupirocin Calcium

MUPIROCIN CALCIUM

Bactroban

Definitions

The calcium salt form of mupirocin, a natural crotonic acid derivative extracted from Pseudomonas fluorescens. Mupirocin inhibits bacterial protein synthesis by specific reversible binding to bacterial isoleucyl tRNA synthase. With excellent activity against gram-positive staphylococci and streptococci, it is primarily used for treatment of primary and secondary skin disorders, nasal infections, and wound healing. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61851

CAS_Registry

115074-43-6

Chemical_Formula

2C26H43O9.Ca.2H2O

code

C61851

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The calcium salt form of mupirocin, a natural crotonic acid derivative extracted from Pseudomonas fluorescens. Mupirocin inhibits bacterial protein synthesis by specific reversible binding to bacterial isoleucyl tRNA synthase. With excellent activity against gram-positive staphylococci and streptococci, it is primarily used for treatment of primary and secondary skin disorders, nasal infections, and wound healing. (NCI04)

FDA_UNII_Code

RG38I2P540

FULL_SYN

Mupirocin Calcium

MUPIROCIN CALCIUM

Bactroban

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29271

label

Mupirocin Calcium

Legacy Concept Name

Mupirocin_Calcium

Preferred_Name

Mupirocin Calcium

prefixIRI

Thesaurus:C61851

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0724641

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28394

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