loading...| Preferred Name | Loperamide | |
| Synonyms |
LOPERAMIDE Loperamide |
|
| Definitions |
A synthetic agent chemically related to the opiates with anti-diarrheal properties. Loperamide decreases gastro-intestinal motility by effects on the circular and longitudinal muscles of the intestine. Part of its anti-diarrheal effect may be due to a reduction of gastro-intestinal secretion produced by opioid receptor binding in the intestinal mucosa. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C618 |
|
| CAS_Registry |
53179-11-6 |
|
| CHEBI_ID |
CHEBI:6532 |
|
| Chemical_Formula |
C29H33ClN2O2 |
|
| code |
C618 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600 |
|
| Contributing_Source |
CTRP FDA HemOnc |
|
| DEFINITION |
A synthetic agent chemically related to the opiates with anti-diarrheal properties. Loperamide decreases gastro-intestinal motility by effects on the circular and longitudinal muscles of the intestine. Part of its anti-diarrheal effect may be due to a reduction of gastro-intestinal secretion produced by opioid receptor binding in the intestinal mucosa. (NCI04) |
|
| Display_Name |
Loperamide |
|
| FDA_UNII_Code |
6X9OC3H4II |
|
| FULL_SYN |
LOPERAMIDE Loperamide |
|
| Has_Salt_Form | ||
| label |
Loperamide |
|
| Legacy Concept Name |
Loperamide |
|
| NSC Number |
696356 |
|
| Preferred_Name |
Loperamide |
|
| prefixIRI |
Thesaurus:C618 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0023992 |
|
| subClassOf |