National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Dipivefrin

Synonyms

DIPIVEFRIN

Dipivefrin

Definitions

An ester prodrug of epinephrine, with sympathomimetic activity. Due to its lipophilicity, dipivefrin penetrates more easily to the anterior chamber of the eye and is hydrolyzed to epinephrine, when applied locally. Epinephrine, an adrenergic agonist, enhances the outflow of aqueous humor and decreases the production of aqueous humor by vasoconstriction. The overall result is a reduction in intraocular pressure.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61729

CAS_Registry

52365-63-6

CHEBI_ID

CHEBI:4646

Chemical_Formula

C19H29NO5

code

C61729

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

An ester prodrug of epinephrine, with sympathomimetic activity. Due to its lipophilicity, dipivefrin penetrates more easily to the anterior chamber of the eye and is hydrolyzed to epinephrine, when applied locally. Epinephrine, an adrenergic agonist, enhances the outflow of aqueous humor and decreases the production of aqueous humor by vasoconstriction. The overall result is a reduction in intraocular pressure.

FDA_UNII_Code

8Q1PVL543G

FULL_SYN

DIPIVEFRIN

Dipivefrin

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47495

label

Dipivefrin

Legacy Concept Name

Dipivefrin

Preferred_Name

Dipivefrin

prefixIRI

Thesaurus:C61729

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0058415

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29705

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