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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Id | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61729
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61729
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|---|---|
| Preferred Name | Dipivefrin |
| Definitions |
An ester prodrug of epinephrine, with sympathomimetic activity. Due to its lipophilicity, dipivefrin penetrates more easily to the anterior chamber of the eye and is hydrolyzed to epinephrine, when applied locally. Epinephrine, an adrenergic agonist, enhances the outflow of aqueous humor and decreases the production of aqueous humor by vasoconstriction. The overall result is a reduction in intraocular pressure.
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| Synonyms |
DIPIVEFRIN
Dipivefrin
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Dipivefrin
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|---|---|
| Legacy Concept Name |
Dipivefrin
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| CHEBI_ID |
CHEBI:4646
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| Preferred_Name |
Dipivefrin
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| Semantic_Type |
Pharmacologic Substance
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| prefixIRI |
Thesaurus:C61729
|
| DEFINITION |
An ester prodrug of epinephrine, with sympathomimetic activity. Due to its lipophilicity, dipivefrin penetrates more easily to the anterior chamber of the eye and is hydrolyzed to epinephrine, when applied locally. Epinephrine, an adrenergic agonist, enhances the outflow of aqueous humor and decreases the production of aqueous humor by vasoconstriction. The overall result is a reduction in intraocular pressure.
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| UMLS_CUI |
C0058415
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| code |
C61729
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| Chemical_Formula |
C19H29NO5
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| subClassOf | |
| type | |
| CAS_Registry |
52365-63-6
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| FULL_SYN |
DIPIVEFRIN
Dipivefrin
|
| FDA_UNII_Code |
8Q1PVL543G
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| Contributing_Source |
FDA
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| Concept_In_Subset | |
| Has_Salt_Form |
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