National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Dinoprostone
Synonyms

DINOPROSTONE

Minprostin E2

Dinoprostone

Dinoglandin

Enzaprost E

Cervidil

Prepidil

Prostin E2

Definitions

A synthetic prostaglandin E2 (PGE2) analogue with smooth muscle contraction inducing property. It has been suggested that PGE2 regulates the intracellular levels of cyclic 3, 5-adenosine monophosphate (cAMP) by activating adenylate cyclase and thereby increases cellular membrane calcium ion transport. By acting directly on the myometrium, dinoprostone induces uterine and gastrointestinal smooth muscle contractions.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61727

CAS_Registry

363-24-6

CHEBI_ID

CHEBI:15551

Chemical_Formula

C20H32O5

code

C61727

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic prostaglandin E2 (PGE2) analogue with smooth muscle contraction inducing property. It has been suggested that PGE2 regulates the intracellular levels of cyclic 3, 5-adenosine monophosphate (cAMP) by activating adenylate cyclase and thereby increases cellular membrane calcium ion transport. By acting directly on the myometrium, dinoprostone induces uterine and gastrointestinal smooth muscle contractions.

FDA_UNII_Code

K7Q1JQR04M

FULL_SYN

DINOPROSTONE

Minprostin E2

Dinoprostone

Dinoglandin

Enzaprost E

Cervidil

Prepidil

Prostin E2

label

Dinoprostone

Legacy Concept Name

Dinoprostone

NCI_Drug_Dictionary_ID

812798

Preferred_Name

Dinoprostone

prefixIRI

Thesaurus:C61727

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0012472

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78568

Delete Subject Author Type Created
No notes to display