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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Id | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61700
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61700
|
|---|---|
| Preferred Name | Desipramine |
| Definitions |
An active metabolite of imipramine, a tertiary amine and a synthetic tricyclic derivative of the antidepressant. Desipramine enhances monoamine neurotransmission in certain areas of the brain by inhibiting the re-uptake of noradrenaline and serotonin at the noradrenergic and serotoninergic nerve endings, respectively. It also induces sedation through histamine 1 receptor blockage and hypotension through beta-adrenergic blockage.
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| Synonyms |
Desipramine
DESIPRAMINE
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label | Desipramine
|
|---|---|
| Legacy Concept Name | Desipramine
|
| CHEBI_ID | CHEBI:47781
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| Preferred_Name | Desipramine
|
| Semantic_Type | Pharmacologic Substance
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| prefixIRI | Thesaurus:C61700
|
| DEFINITION | An active metabolite of imipramine, a tertiary amine and a synthetic tricyclic derivative of the antidepressant. Desipramine enhances monoamine neurotransmission in certain areas of the brain by inhibiting the re-uptake of noradrenaline and serotonin at the noradrenergic and serotoninergic nerve endings, respectively. It also induces sedation through histamine 1 receptor blockage and hypotension through beta-adrenergic blockage.
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| UMLS_CUI | C0011685
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| code | C61700
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| Chemical_Formula | C18H22N2
|
| subClassOf | |
| type | |
| CAS_Registry | 50-47-5
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| FULL_SYN |
Desipramine
DESIPRAMINE
|
| FDA_UNII_Code | TG537D343B
|
| Contributing_Source | FDA
|
| Concept_In_Subset | |
| Has_Salt_Form |
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| /ontologies/NCIT/notes/https%3A%2F%2Fdata.bioontology.org%2Fnotes%2F8dfd5db0-bd90-0136-3c5b-005056010073 | tabasco_tabata%40yahoo.co.jp | Comment | 2018-10-29 | |
| New concept - total skin sparing mastectomy | anonymous | Comment | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C15277 | 2013-05-22 |
| RE: Antineoplastic antibiotics are antibiotics (?) | rwynne | Comment | 2013-02-13 | |
| Antineoplastic antibiotics are antibiotics (?) | coulet | Comment | 2013-01-25 | |
| Test note | decorons | Comment | 2011-02-07 | |
| New Term Proposal: abcd | fergerson | New Class Proposal | 2010-12-17 | |
| relationship with Smoking Behavior | pkcourtney | Comment | 2010-06-22 | |
| causes and symptoms | linairis | Comment | 2009-08-06 | |
| NIH-What Causes COPD | linairis | Comment | 2009-08-06 | |
| The treatment of COPD | linairis | Comment | 2009-08-06 | |
| MedlinePlus | linairis | Comment | 2009-08-06 | |
| decorons | Comment | 2008-12-31 | ||
| decorons | Comment | 2008-12-31 | ||
| decorons | Comment | 2008-12-31 | ||
| decorons | Comment | 2008-12-31 | ||
| An image example for melanoma | jonquet | Comment | 2008-08-06 | |
| Wikipedia page on 'melanoma' | jonquet | Comment | 2008-08-06 |
Showing 1 to 17 of 17 entries
