National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Inosine Pranobex

Synonyms

Isoprinosin

INOSINE PRANOBEX

Isoprinosine

Inosine Mono[4-(acetylamino)benzoate] Salt Compd with 1-(dimethylamino)-2-propanol(1:3)

Inosine Pranobex

Inosine:Dimethylaminoisopropanol Acetamidobenzoate(1:3)

Methisoprinol

Isoprinosina

Aviral

Delimmun

Imunovir

Inosiplex

NP-113

NPT 10381

NPT-10381

Pranosina

Pranosine

Viruxan

Definitions

A formulation containing inosine, 4-acetamidobenzoic Acid, and N,N-dimethylaminoisopropanol, with immunomodulatory and antiviral activities. Although the exact mechanism of action is unknown, inosine pranobex appears to act as a thymus hormone analog; following administration, this agent may both induce T-cell differentiation and potentiate lymphoproliferative responses against transformed or virally-infected cells.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C601

CAS_Registry

36703-88-5

Chemical_Formula

C10H12N4O5.3C9H9NO3.3C5H13NO

code

C601

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A formulation containing inosine, 4-acetamidobenzoic Acid, and N,N-dimethylaminoisopropanol, with immunomodulatory and antiviral activities. Although the exact mechanism of action is unknown, inosine pranobex appears to act as a thymus hormone analog; following administration, this agent may both induce T-cell differentiation and potentiate lymphoproliferative responses against transformed or virally-infected cells.

FDA_UNII_Code

W1SO0V223F

FULL_SYN

Isoprinosin

INOSINE PRANOBEX

Isoprinosine

Inosine Mono[4-(acetylamino)benzoate] Salt Compd with 1-(dimethylamino)-2-propanol(1:3)

Inosine Pranobex

Inosine:Dimethylaminoisopropanol Acetamidobenzoate(1:3)

Methisoprinol

Isoprinosina

Aviral

Delimmun

Imunovir

Inosiplex

NP-113

NPT 10381

NPT-10381

Pranosina

Pranosine

Viruxan

label

Inosine Pranobex

Legacy Concept Name

Inosine_Pranobex

NCI_Drug_Dictionary_ID

39487

PDQ_Closed_Trial_Search_ID

39487

PDQ_Open_Trial_Search_ID

39487

Preferred_Name

Inosine Pranobex

prefixIRI

Thesaurus:C601

Semantic_Type

Pharmacologic Substance

Nucleic Acid, Nucleoside, or Nucleotide

UMLS_CUI

C0022230

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2139

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Delete Mapping To Ontology Source
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D007542 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/D007542 MESH LOOM
http://purl.jp/bio/4/id/200906023512758084 IOBC LOOM
http://purl.obolibrary.org/obo/NCIT_C601 BERO LOOM
http://stirdf.jst.go.jp/id/200907048345433263 IOBC LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015826 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039487 PDQ LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D13.570.583.616.450 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/395749001 SNOMEDCT LOOM
https://go.drugbank.com/drugs/DB13156 MDM LOOM
http://purl.obolibrary.org/obo/DRON_00017152 PDRO LOOM
http://purl.obolibrary.org/obo/DRON_00017152 DRON LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#6961 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.199.092.450 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/6048 RXNORM LOOM
http://purl.bioontology.org/ontology/NDDF/003902 NDDF LOOM
http://purl.bioontology.org/ontology/RCD/ei3.. RCD LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0022230 OCHV LOOM
http://purl.bioontology.org/ontology/ATC/J05AX05 ATC LOOM
http://www.co-ode.org/ontologies/galen#InosinePranobex GALEN LOOM
http://purl.obolibrary.org/obo/OMIT_0008657 OMIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D13.570.800.573.450 RH-MESH LOOM
http://purl.obolibrary.org/obo/MESH_D007542 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.759.590.616.450 RH-MESH LOOM