loading...| Preferred Name |
Oxitriptan |
|
| Synonyms |
5-Hydroxytryptophan L-5-Hydroxytryptophan 2-Amino-3-(5-hydroxy-1-H-indol-3-yl)propionic Acid 5-HTP Levothym OXITRIPTAN Oxitriptan Oxyfan Pretonine Quietim Serotonyl Telesol |
|
| Definitions |
An aromatic amino acid with antidepressant activity. In vivo, oxitriptan (or 5-hydroxytryptophan) is converted into 5-hydroxytryptamine (5-HT or serotonin) as well as other neurotransmitters. Oxitriptan may exert its antidepressant activity via conversion to serotonin or directly by binding to serotonin (5-HT) receptors within the central nervous system (CNS). Endogenous oxitriptan is produced from the essential amino acid L-tryptophan. The exogenous therapeutic form is isolated from the seeds of the African plant Griffonia simplicifolia. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C52181 |
|
| CAS_Registry |
4350-09-8 |
|
| CHEBI_ID |
CHEBI:17780 |
|
| Chemical_Formula |
C11H12N2O3 |
|
| code |
C52181 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
An aromatic amino acid with antidepressant activity. In vivo, oxitriptan (or 5-hydroxytryptophan) is converted into 5-hydroxytryptamine (5-HT or serotonin) as well as other neurotransmitters. Oxitriptan may exert its antidepressant activity via conversion to serotonin or directly by binding to serotonin (5-HT) receptors within the central nervous system (CNS). Endogenous oxitriptan is produced from the essential amino acid L-tryptophan. The exogenous therapeutic form is isolated from the seeds of the African plant Griffonia simplicifolia. |
|
| FDA_UNII_Code |
C1LJO185Q9 |
|
| FULL_SYN |
5-Hydroxytryptophan L-5-Hydroxytryptophan 2-Amino-3-(5-hydroxy-1-H-indol-3-yl)propionic Acid 5-HTP Levothym OXITRIPTAN Oxitriptan Oxyfan Pretonine Quietim Serotonyl Telesol |
|
| label |
Oxitriptan |
|
| Legacy Concept Name |
_5-Hydroxytryptophan |
|
| NCI_Drug_Dictionary_ID |
459776 |
|
| PDQ_Closed_Trial_Search_ID |
459776 |
|
| PDQ_Open_Trial_Search_ID |
459776 |
|
| Preferred_Name |
Oxitriptan |
|
| prefixIRI |
Thesaurus:C52181 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0000578 |
|
| subClassOf |