loading...| Preferred Name |
Folate Antagonist |
|
| Synonyms |
Folic Acid Antagonists Folic Acid Antagonist Folic Acid Analog folate antagonist Antifolates Folate Inhibitors Folate Analog Folic Acid Inhibitors Folate Antagonist antifolate |
|
| Definitions |
A compound with a chemical structure similar to folic acid. Folate antagonists inhibit one or more folate-dependent enzymes, resulting in decreased DNA, RNA and protein synthesis. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C511 |
|
| ALT_DEFINITION |
A substance that blocks the activity of folic acid. Folate antagonists are used to treat cancer. |
|
| code |
C511 |
|
| DEFINITION |
A compound with a chemical structure similar to folic acid. Folate antagonists inhibit one or more folate-dependent enzymes, resulting in decreased DNA, RNA and protein synthesis. |
|
| FULL_SYN |
Folic Acid Antagonists Folic Acid Antagonist Folic Acid Analog folate antagonist Antifolates Folate Inhibitors Folate Analog Folic Acid Inhibitors Folate Antagonist antifolate |
|
| label |
Folate Antagonist |
|
| Legacy Concept Name |
Folate_Antagonist |
|
| Preferred_Name |
Folate Antagonist |
|
| prefixIRI |
Thesaurus:C511 |
|
| Semantic_Type |
Chemical Viewed Functionally |
|
| UMLS_CUI |
C0016411 |
|
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/CSP/1174-5583 | CRISP | LOOM | |
| http://purl.bioontology.org/ontology/npo#NPO_460 | NPO | LOOM | |
| http://purl.obolibrary.org/obo/NCIT_C511 | BERO | LOOM |