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National Cancer Institute Thesaurus
| Preferred Name | Folic Acid | |
| Synonyms |
N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid 2-[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]aminopentanedioic acid Pteroylmonoglutamic Acid N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid FA FOLIC ACID Ffolate Folacin Folic Acid Folic acid Vitamin B9 Vitamin Bc folic acid |
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| Definitions |
A collective term for pteroylglutamic acids and their oligoglutamic acid conjugates. As a natural water-soluble substance, folic acid is involved in carbon transfer reactions of amino acid metabolism, in addition to purine and pyrimidine synthesis, and is essential for hematopoiesis and red blood cell production. (NCI05) |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C510 |
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| ALT_DEFINITION |
Synthetic folate in fortified foods and supplements containing a single glutamate molecule. A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Folate helps to make red blood cells. It is found in whole-grain breads and cereals, liver, green vegetables, orange juice, lentils, beans, and yeast. Folate is water-soluble (can dissolve in water) and must be taken in every day. Not enough folate can cause anemia (a condition in which the number of red blood cells is below normal), diseases of the heart and blood vessels, and defects in the brain and spinal cord in a fetus. Folate is being studied with vitamin B12 in the prevention and treatment of cancer.
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| CAS_Registry |
59-30-3
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| CHEBI_ID |
CHEBI:27470
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| Chemical_Formula |
C19H19N7O6
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| code |
C510
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
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| Contributing_Source |
CRCH CTRP FDA GDC HemOnc
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| DEFINITION |
A collective term for pteroylglutamic acids and their oligoglutamic acid conjugates. As a natural water-soluble substance, folic acid is involved in carbon transfer reactions of amino acid metabolism, in addition to purine and pyrimidine synthesis, and is essential for hematopoiesis and red blood cell production. (NCI05)
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| Display_Name |
Folic Acid
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| FDA_UNII_Code |
935E97BOY8
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| FULL_SYN |
N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid 2-[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]aminopentanedioic acid Pteroylmonoglutamic Acid N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid FA FOLIC ACID Ffolate Folacin Folic Acid Folic acid Vitamin B9 Vitamin Bc folic acid
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| INFOODS |
FOLAC
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| Is_Value_For_GDC_Property | ||
| label |
Folic Acid
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| Legacy Concept Name |
Folic_Acid
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| Maps_To |
Folic Acid
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| NCI_Drug_Dictionary_ID |
39641
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| NSC Number |
3073
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| PDQ_Closed_Trial_Search_ID |
39641
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| PDQ_Open_Trial_Search_ID |
39641
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| Preferred_Name |
Folic Acid
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| prefixIRI |
Thesaurus:C510
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| Semantic_Type |
Organic Chemical Vitamin
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| Tolerable_Level |
Y
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| UMLS_CUI |
C0016410
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| Unit |
mcg
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| US_Recommended_Intake |
Y* (*for women of childbearing age)
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| USDA_ID |
431
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| subClassOf |
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