National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Endotoxin

Synonyms

Bacterial Pyrogen

Endotoxin

Endotoxins

Definitions

The lipopolysaccharide complexes that are part of the outer membrane of the cell wall of Gram-negative bacteria such as E. coli, Salmonella, Shigella, Pseudomonas, Neisseria, Haemophilus, and other leading pathogens. Upon bacterial infections, the lipid component (Lipid A) of endotoxin contributes to its toxicity, while the polysaccharide components contribute to immunogenicity.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C50918

code

C50918

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

The lipopolysaccharide complexes that are part of the outer membrane of the cell wall of Gram-negative bacteria such as E. coli, Salmonella, Shigella, Pseudomonas, Neisseria, Haemophilus, and other leading pathogens. Upon bacterial infections, the lipid component (Lipid A) of endotoxin contributes to its toxicity, while the polysaccharide components contribute to immunogenicity.

Display_Name

Endotoxin

FULL_SYN

Bacterial Pyrogen

Endotoxin

Endotoxins

label

Endotoxin

Legacy Concept Name

Endotoxin

Preferred_Name

Endotoxin

prefixIRI

Thesaurus:C50918

Semantic_Type

Organic Chemical

UMLS_CUI

C0014264

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C296

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