National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Ciprofloxacin Hydrochloride

Synonyms

Ciprofloxacin Hydrochloride

1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid, Monohydrochloride, Monohydrate

CIPROFLOXACIN HYDROCHLORIDE

Ciloxan

Definitions

The hydrochloride salt form of ciprofloxacin, a fluoroquinolone related to nalidixic acid with antibacterial activity. Ciprofloxacin hydrochloride exerts its bactericidal effect by interfering with the bacterial DNA gyrase, thereby inhibiting the DNA synthesis and preventing bacterial cell growth.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47976

CAS_Registry

86393-32-0

CHEBI_ID

CHEBI:59936

Chemical_Formula

C17H18FN3O3.HCl.H2O

code

C47976

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The hydrochloride salt form of ciprofloxacin, a fluoroquinolone related to nalidixic acid with antibacterial activity. Ciprofloxacin hydrochloride exerts its bactericidal effect by interfering with the bacterial DNA gyrase, thereby inhibiting the DNA synthesis and preventing bacterial cell growth.

FDA_UNII_Code

4BA73M5E37

FULL_SYN

Ciprofloxacin Hydrochloride

1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid, Monohydrochloride, Monohydrate

CIPROFLOXACIN HYDROCHLORIDE

Ciloxan

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C375

label

Ciprofloxacin Hydrochloride

Legacy Concept Name

Ciprofloxacin_Hydrochloride

NSC Number

620634

Preferred_Name

Ciprofloxacin Hydrochloride

prefixIRI

Thesaurus:C47976

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0282104

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C280

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C795

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