loading...| Preferred Name | Therapeutic Estradiol | |
| Synonyms |
(17beta)-Estra-1,3,5(10)-triene-3,17-diol 17 Beta-Estradiol Dimenformon Therapeutic Estradiol Aquadiol Climara Diogyn Diogynets ESTRADIOL Estrace Estraldine Oestradiol Ovocylin Progynon Vagifem |
|
| Definitions |
A synthetic form of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females, that may be used as hormone replacement therapy. Typically esterified, estradiol derivatives are formulated for oral, intravaginal, transdermal, or parenteral administration. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. Estradiol exhibits mild anabolic and metabolic properties, and increases blood coagulability. It may play a role in immune and inflammatory processes. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C478 |
|
| CAS_Registry |
50-28-2 |
|
| CHEBI_ID |
CHEBI:16469 |
|
| Chemical_Formula |
C18H24O2 |
|
| code |
C478 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
|
| Contributing_Source |
CTRP FDA GDC |
|
| DEFINITION |
A synthetic form of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females, that may be used as hormone replacement therapy. Typically esterified, estradiol derivatives are formulated for oral, intravaginal, transdermal, or parenteral administration. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. Estradiol exhibits mild anabolic and metabolic properties, and increases blood coagulability. It may play a role in immune and inflammatory processes. |
|
| Display_Name |
Therapeutic Estradiol |
|
| FDA_UNII_Code |
4TI98Z838E |
|
| FULL_SYN |
(17beta)-Estra-1,3,5(10)-triene-3,17-diol 17 Beta-Estradiol Dimenformon Therapeutic Estradiol Aquadiol Climara Diogyn Diogynets ESTRADIOL Estrace Estraldine Oestradiol Ovocylin Progynon Vagifem |
|
| Has_Target | ||
| Is_Value_For_GDC_Property | ||
| label |
Therapeutic Estradiol |
|
| Legacy Concept Name |
Therapeutic_Estradiol |
|
| Maps_To |
Therapeutic Estradiol |
|
| NCI_Drug_Dictionary_ID |
39236 |
|
| NSC Number |
20293 9895 |
|
| PDQ_Closed_Trial_Search_ID |
39236 |
|
| PDQ_Open_Trial_Search_ID |
39236 |
|
| Preferred_Name |
Therapeutic Estradiol |
|
| prefixIRI |
Thesaurus:C478 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0699359 |
|
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/NCIT_C478 | BERO | LOOM | |
| http://purl.obolibrary.org/obo/NCIT_C478 | GSSO | LOOM | |
| http://purl.bioontology.org/ontology/PDQ/CDR0000039236 | PDQ | LOOM |