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National Cancer Institute Thesaurus
| Preferred Name | Tubocurarine Chloride | |
| Synonyms |
Tubocuraranium, 7',12'-Dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyl-, Chloride, Hydrochloride TUBOCURARINE CHLORIDE 2,3,13a,14,15,16,25,25a-Octahydro-9,19-dihydroxy-18,29-dimethoxy-1,14,14-trimethyl-, Chloride, Hydrochloride,(13aR,25aS)- d-Tubocurarine Chloride Pentahydrate 13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido(3',2':14,15)(1,11)dioxacycloeicosino(2,3,4-ij)isoquinolinium Tubocurarine Chloride Tubocuraranium, 7',12'-Dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyl-, Chloride, Hydrochloride, Pentahydrate Tubocurarine, Dichloride, Pentahydrate, (+)- Amerizol Tubocurare |
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| Definitions |
The chloride salt form of tubocurarine, a naturally occurring curare alkaloid isolated from the bark and stem of Chondodendron tomentosum with a muscle relaxant property. Tubocurarine chloride competes with acetylcholine for the nicotinic receptors at the neuromuscular junction of skeletal muscles, thereby inhibiting the action of acetylcholine and blocking the neural transmission without depolarizing the postsynaptic membrane. This may lead to skeletal muscle relaxation and paralysis. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47777 |
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| CAS_Registry |
6989-98-6
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| Chemical_Formula |
C37H41N2O6.Cl.HCl.5H2O
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| code |
C47777
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| Concept_In_Subset | ||
| Contributing_Source |
FDA
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| DEFINITION |
The chloride salt form of tubocurarine, a naturally occurring curare alkaloid isolated from the bark and stem of Chondodendron tomentosum with a muscle relaxant property. Tubocurarine chloride competes with acetylcholine for the nicotinic receptors at the neuromuscular junction of skeletal muscles, thereby inhibiting the action of acetylcholine and blocking the neural transmission without depolarizing the postsynaptic membrane. This may lead to skeletal muscle relaxation and paralysis.
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| FDA_UNII_Code |
900961Z8VR
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| FULL_SYN |
Tubocuraranium, 7',12'-Dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyl-, Chloride, Hydrochloride TUBOCURARINE CHLORIDE 2,3,13a,14,15,16,25,25a-Octahydro-9,19-dihydroxy-18,29-dimethoxy-1,14,14-trimethyl-, Chloride, Hydrochloride,(13aR,25aS)- d-Tubocurarine Chloride Pentahydrate 13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido(3',2':14,15)(1,11)dioxacycloeicosino(2,3,4-ij)isoquinolinium Tubocurarine Chloride Tubocuraranium, 7',12'-Dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyl-, Chloride, Hydrochloride, Pentahydrate Tubocurarine, Dichloride, Pentahydrate, (+)- Amerizol Tubocurare
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| label |
Tubocurarine Chloride
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| Legacy Concept Name |
Tubocurarine_Chloride
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| NSC Number |
36387
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| Preferred_Name |
Tubocurarine Chloride
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| prefixIRI |
Thesaurus:C47777
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0282372
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| subClassOf |
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