National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Spectinomycin Hydrochloride
Synonyms

Spectinomycin Hydrochloride Anhydrous

4H-Pyrano(2,3-b)(1,4)benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, Dihydrochloride,(2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-

Spectinomycin Dihydrochloride

SPECTINOMYCIN HYDROCHLORIDE

Spectinomycin Hydrochloride

Spectogard

Trobicin

Definitions

The hydrochloride salt form of spectinomycin, an aminocyclitol antibiotic derived from Streptomyces spectabilis with antibacterial property. Spectinomycin hydrochloride binds to the bacterial 30S ribosomal subunit, thereby inhibiting peptide elongation and protein synthesis, consequently leading to bacterial cell death.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47728

CAS_Registry

22189-32-8

Chemical_Formula

C14H24N2O7.2HCl.5H2O

code

C47728

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The hydrochloride salt form of spectinomycin, an aminocyclitol antibiotic derived from Streptomyces spectabilis with antibacterial property. Spectinomycin hydrochloride binds to the bacterial 30S ribosomal subunit, thereby inhibiting peptide elongation and protein synthesis, consequently leading to bacterial cell death.

FDA_UNII_Code

HWT06H303Z

FULL_SYN

Spectinomycin Hydrochloride Anhydrous

4H-Pyrano(2,3-b)(1,4)benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, Dihydrochloride,(2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-

Spectinomycin Dihydrochloride

SPECTINOMYCIN HYDROCHLORIDE

Spectinomycin Hydrochloride

Spectogard

Trobicin

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61951

label

Spectinomycin Hydrochloride

Legacy Concept Name

Spectinomycin_Hydrochloride

NSC Number

248616

Preferred_Name

Spectinomycin Hydrochloride

prefixIRI

Thesaurus:C47728

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0887525

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2363

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