National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Naphazoline Hydrochloride
Synonyms

Naphazoline Hydrochloride

2-(1-Naphthylmethyl)-2-imidazoline Hydrochloride

NAPHAZOLINE HYDROCHLORIDE

1H-Imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)-, Monohydrochloride

Albalon

Nafazair

Opcon

Vasocon

Definitions

The hydrochloride salt form of naphazoline, an imidazole derivative and a direct-acting sympathomimetic amine with vasoconstrictive properties. Upon ocular administration, naphazoline hydrochloride exerts its effect by acting on alpha-adrenergic receptors in the arterioles of the conjunctiva to produce vasoconstriction, resulting in decreased conjunctival congestion and diminished itching, irritation and redness.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47632

CAS_Registry

550-99-2

Chemical_Formula

C14H14N2.HCl

code

C47632

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The hydrochloride salt form of naphazoline, an imidazole derivative and a direct-acting sympathomimetic amine with vasoconstrictive properties. Upon ocular administration, naphazoline hydrochloride exerts its effect by acting on alpha-adrenergic receptors in the arterioles of the conjunctiva to produce vasoconstriction, resulting in decreased conjunctival congestion and diminished itching, irritation and redness.

FDA_UNII_Code

MZ1131787D

FULL_SYN

Naphazoline Hydrochloride

2-(1-Naphthylmethyl)-2-imidazoline Hydrochloride

NAPHAZOLINE HYDROCHLORIDE

1H-Imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)-, Monohydrochloride

Albalon

Nafazair

Opcon

Vasocon

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61856

label

Naphazoline Hydrochloride

Legacy Concept Name

Naphazoline_Hydrochloride

NSC Number

35711

Preferred_Name

Naphazoline Hydrochloride

prefixIRI

Thesaurus:C47632

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0721921

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29709

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