loading...| Preferred Name | Levonordefrin | |
| Synonyms |
LEVONORDEFRIN 1,2-Benzenediol, 4-(2-amino-1-hydroxypropyl)-,(R-(R*,S*))- Levonordefrin Neo-Cobefrin (-)-alpha-(1-Aminoethyl)-3,4-dihydroxybenzyl Alcohol |
|
| Definitions |
The levoisomer of nordefrin, a synthetic catecholamine and norepinephrine derivative with sympathomimetic and antihypertensive effects. Levonordefrin's antihypertensive effect is exerted through activation of alpha 2-adrenergic receptors in the cardiovascular control center of the CNS thereby suppressing the sympathetic output from the brain and subsequently lowering blood pressure. Levonordefrin binds to and activates peripheral alpha 2- adrenergic receptors, thereby causing vasoconstriction. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47584 |
|
| CAS_Registry |
18829-78-2 829-74-3 |
|
| Chemical_Formula |
C9H13NO3 |
|
| code |
C47584 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
The levoisomer of nordefrin, a synthetic catecholamine and norepinephrine derivative with sympathomimetic and antihypertensive effects. Levonordefrin's antihypertensive effect is exerted through activation of alpha 2-adrenergic receptors in the cardiovascular control center of the CNS thereby suppressing the sympathetic output from the brain and subsequently lowering blood pressure. Levonordefrin binds to and activates peripheral alpha 2- adrenergic receptors, thereby causing vasoconstriction. |
|
| FDA_UNII_Code |
V008L6478D |
|
| FULL_SYN |
LEVONORDEFRIN 1,2-Benzenediol, 4-(2-amino-1-hydroxypropyl)-,(R-(R*,S*))- Levonordefrin Neo-Cobefrin (-)-alpha-(1-Aminoethyl)-3,4-dihydroxybenzyl Alcohol |
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| Has_Salt_Form | ||
| label |
Levonordefrin |
|
| Legacy Concept Name |
Levonordefrin |
|
| Preferred_Name |
Levonordefrin |
|
| prefixIRI |
Thesaurus:C47584 |
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| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0520472 |
|
| subClassOf |