National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Levocabastine Hydrochloride

Synonyms

LEVOCABASTINE HYDROCHLORIDE

4-Piperidinecarboxylic Acid, 1-(4-cyano-4-(4-fluorophenyl)cyclohexyl)-3-methyl-4-phenyl-, Monohydrochloride,(-)-(1(cis)3alpha,4beta)-

Levocabastine Hydrochloride

Livostin

R 50,547

Definitions

The hydrochloride salt form of levocabastine, a synthetic piperidine derivative with antihistaminic properties. Levocabastine is a second generation histamine-1 receptor antagonist. When applied locally to the eye as a topical solution, this agent reduces itching, rhinorrhea, and symptoms of allergic rhinitis or conjunctivitis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47582

CAS_Registry

79547-78-7

Chemical_Formula

C26H29FN2O2.HCl

code

C47582

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The hydrochloride salt form of levocabastine, a synthetic piperidine derivative with antihistaminic properties. Levocabastine is a second generation histamine-1 receptor antagonist. When applied locally to the eye as a topical solution, this agent reduces itching, rhinorrhea, and symptoms of allergic rhinitis or conjunctivitis.

FDA_UNII_Code

124XMA6YEI

FULL_SYN

LEVOCABASTINE HYDROCHLORIDE

4-Piperidinecarboxylic Acid, 1-(4-cyano-4-(4-fluorophenyl)cyclohexyl)-3-methyl-4-phenyl-, Monohydrochloride,(-)-(1(cis)3alpha,4beta)-

Levocabastine Hydrochloride

Livostin

R 50,547

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61806

label

Levocabastine Hydrochloride

Legacy Concept Name

Levocabastine_Hydrochloride

Preferred_Name

Levocabastine Hydrochloride

prefixIRI

Thesaurus:C47582

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0244861

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29578

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