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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Id | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47551
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47551
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|---|---|
| Preferred Name | Guanidine Hydrochloride |
| Definitions |
The hydrochloride salt form of guanidine, a strong basic compound with parasympathomimetic activity. Guanidine hydrochloride enhances the release of acetylcholine following a nerve impulse and potentiates acetylcholine actions on muscarinic and nicotinic receptors. It also appears to slow the rates of depolarization and repolarization of muscle cell membranes. (NCI05)
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| Synonyms |
Aminoformamidine Hydrochloride
Guanidinium Chloride
GUANIDINE HYDROCHLORIDE
Guanidine Hydrochloride
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Guanidine Hydrochloride
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|---|---|
| Legacy Concept Name |
Guanidine_Hydrochloride
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| CHEBI_ID |
CHEBI:32735
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| Preferred_Name |
Guanidine Hydrochloride
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| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| prefixIRI |
Thesaurus:C47551
|
| DEFINITION |
The hydrochloride salt form of guanidine, a strong basic compound with parasympathomimetic activity. Guanidine hydrochloride enhances the release of acetylcholine following a nerve impulse and potentiates acetylcholine actions on muscarinic and nicotinic receptors. It also appears to slow the rates of depolarization and repolarization of muscle cell membranes. (NCI05)
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| UMLS_CUI |
C0120447
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| code |
C47551
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| Chemical_Formula |
CH5N3.HCl
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| subClassOf | |
| type | |
| CAS_Registry |
50-01-1
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| FULL_SYN |
Aminoformamidine Hydrochloride
Guanidinium Chloride
GUANIDINE HYDROCHLORIDE
Guanidine Hydrochloride
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| FDA_UNII_Code |
3YQC9ZY4YB
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| Contributing_Source |
FDA
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| Concept_In_Subset | |
| Has_Free_Acid_Or_Base_Form |
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